Evidence map›Paper›PMID 33097556›Full record

ArticleDisease models & mechanisms2020

CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons.

S Schuster, E Heuten, A Velic, J Admard, M Synofzik, S Ossowski, B Macek, S Hauser, L Schöls

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CAPRIN1Cellular and molecular life sciences : CMLS · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

S SchusterDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
E HeutenDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
A VelicProteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.
J AdmardInstitute for Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany.
M SynofzikDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
S OssowskiInstitute for Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany.
B MacekProteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.
S HauserDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany stefan.hauser@dzne.de ludger.schoels@uni-tuebingen.de.ORCID 0000-0002-1022-7482
L SchölsDepartment of Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany stefan.hauser@dzne.de ludger.schoels@uni-tuebingen.de.ORCID 0000-0001-7774-5025
University of Tübingen · DEGerman Center for Neurodegenerative Diseases · DEHertie Institute for Clinical Brain Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-terminus of HSC70-interacting protein (CHIP) encoded by the gene

Indexed as

BiomarkersCell SurvivalFibroblastsHeat-Shock ResponseHumansInduced Pluripotent Stem CellsMutationNeuronsOxidative StressProtein RefoldingProteomeUbiquitinationUbiquitin-Protein LigasesBiomarkersProteomeSTUB1 protein, humanUbiquitin-Protein LigasesCHIP/STUB1Cortical neuronsCRISPR/Cas9Heat shock responseInduced pluripotent stem cellsSCAR16

Identifiers

PMID33097556
PMCPMC7578354
OpenAlexW3092979842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.