Evidence map›Paper›PMID 33097498›Full record

ArticleApplied and environmental microbiology2020

Fragment Exchange Plasmid Tools for CRISPR/Cas9-Mediated Gene Integration and Protease Production in Bacillus subtilis.

Antonio García-Moyano, Øivind Larsen, Sushil Gaykawad, Eleni Christakou, Catherine Boccadoro, Pål Puntervoll, Gro Elin Kjæreng Bjerga

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Highly efficient genome editing inSynthetic and systems biotechnology · 2025
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  11. Advances in Enhanced Menaquinone-7 Production FromFrontiers in bioengineering and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antonio García-MoyanoNORCE Norwegian Research Centre, Bergen, Norway.ORCID 0000-0003-1997-8589
Øivind LarsenNORCE Norwegian Research Centre, Bergen, Norway.
Sushil GaykawadNORCE Norwegian Research Centre, Bergen, Norway.
Eleni ChristakouNORCE Norwegian Research Centre, Bergen, Norway.
Catherine BoccadoroNORCE Norwegian Research Centre, Bergen, Norway.
Pål PuntervollNORCE Norwegian Research Centre, Bergen, Norway.
Gro Elin Kjæreng BjergaNORCE Norwegian Research Centre, Bergen, Norway gro.bjerga@norceresearch.no.ORCID 0000-0001-5152-5139
NORCE Research AS · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its discovery as part of the bacterial adaptative immune system, CRISPR/Cas has emerged as the most promising tool for targeted genome editing over the past few years. Various tools for genome editing in

Indexed as

CRISPR-Cas SystemsGene EditingBacillus subtilisPeptide HydrolasesPlasmidsPeptide HydrolasesBacillus subtilisCRISPRFX cloninggenome editingmicrobial fermentationproteasesubtilisin

Identifiers

PMID33097498
PMCPMC7755240
OpenAlexW3093720428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.