Evidence map›Paper›PMID 33097032›Full record

ArticleBMC public health2020

Characterization of HIV risks in a Brazilian sickle cell disease population.

P F Blatyta, S Kelly, T T Goncalez, A B Carneiro-Proietti, T Salomon, C Miranda, E Sabino, L Preiss, C Maximo, P Loureiro and 3 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

P F BlatytaHospital Moysés Deutsch, São Paulo, SP, Brazil. pblatyta@yahoo.com.br.ORCID http://orcid.org/0000-0002-2026-9811
S KellyVitalant Research Institute, San Francisco, CA, USA.
T T GoncalezVitalant Research Institute, San Francisco, CA, USA.
A B Carneiro-ProiettiFundação Hemominas, Belo Horizonte, MG, Brazil.
T SalomonFundação Hemominas, Belo Horizonte, MG, Brazil.
C MirandaFundação Hemominas, Belo Horizonte, MG, Brazil.
E SabinoInstituto de Medicina Tropical da FMUSP, São Paulo, SP, Brazil.
L PreissResearch Triangle Institute, International, Rockville, MD, USA.
C MaximoHemorio, Rio de Janeiro, RJ, Brazil.
P LoureiroFundação Hemope and Universidade de Pernambuco, Recife, PE, Brazil.
B CusterVitalant Research Institute, San Francisco, CA, USA.
C de Almeida-NetoDisciplina de Ciências Médicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) International Component, Brazil
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais · BRPacific Research Institute · USFundação Hemopa · BRHemorio · BRInstituto de Medicina Avançada · BRRTI International · USUniversidade de São Paulo · BRYahoo (Spain) · ES

Funding

NHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007I
6 · The paper itself

Abstract

backgroundA low prevalence of HIV in sickle cell disease (SCD) patients has been reported in the literature though mechanisms for this are not understood.

methodsHIV risk behaviors were compared between SCD cases and non-SCD controls using a self-administered audio computer-assisted self-interview. SCD cases were recruited from a multi-center SCD cohort established in Brazil; controls were recruited from SCD social contacts. Categorical variables were analyzed using Chi-Square or Fisher exact test. Continuous variables were compared using the Mann-Whitney U test.

resultsThere were 152 SCD cases and 154 age/location matched controls enrolled at three participating Brazilian centers during 2016-17. No significant differences in number of sexual partners (lifetime or previous 12 months), male-to-male sex partners or intravenous drug use were observed. Cases received more transfusions, surgeries, and acupuncture treatment.

conclusionsBesides the risk of transfusion-transmitted HIV, which is now exceedingly rare, SCD and non-SCD participants demonstrated similar HIV risk behaviors. Causes other than risk behaviors such as factors inherent to SCD pathophysiology may explain the reported low prevalence of HIV in SCD.

Indexed as

Health Risk BehaviorsAdolescentAdultAgedAnemia, Sickle CellBlood TransfusionBrazilCase-Control StudiesCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceSexual PartnersHIVHIV risk factorsSickle cell diseaseTransfusion transmitted infections

Identifiers

PMID33097032
PMCPMC7585195
OpenAlexW3094351366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.