Evidence map›Paper›PMID 33097025›Full record

Observational studyBMC pregnancy and childbirth2020

Impact of temperature change from admission to day one on neonatal mortality in a low-resource setting.

Francesco Cavallin, Serena Calgaro, Valentina Brugnolaro, Amir Hussein Abubacar Seni, Arlindo Rosario Muhelo, Liviana Da Dalt, Giovanni Putoto, Daniele Trevisanuto

2 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06000826 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Efficacy of a Low-cost Warming Mattress Celsi Warmer for the Management of Hypothermic Newborns

TypeinterventionalSponsorWilliam Marsh Rice UniversityRan2022 to 2024Enrolled90ConditionsNewborn HypothermiaArmsCelsi Warmer
NCT06003140 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy of Low-cost Warming Mattress Celsi Warmer for the Management of Hypothermic Newborns at the Lagos University Teaching Hospital in Lagos, Nigeria

TypeinterventionalSponsorWilliam Marsh Rice UniversityRan2023 to 2024Enrolled90ConditionsNeonatal HypothermiaArmsCelsi Warmer
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Polyethylene bags before cord clamping in very preterm infants: a randomised controlled trial.Archives of disease in childhood. Fetal and neonatal edition · 2024
    Trial
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Quality Improvement Intervention Lowers Hypothermia Rates in Preterm Infants in a Resource-Limited Setting.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco CavallinIndependent statistician, Solagna, Italy.
Serena CalgaroDoctors with Africa CUAMM, Padova, Italy.
Valentina BrugnolaroDepartment of Women and Children Health, University of Padova, Via Giustiniani, 3, 35128, Padova, Italy.
Amir Hussein Abubacar SeniCentral Hospital of Beira, Beira, Mozambique.
Arlindo Rosario MuheloCentral Hospital of Beira, Beira, Mozambique.
Liviana Da DaltDepartment of Women and Children Health, University of Padova, Via Giustiniani, 3, 35128, Padova, Italy.
Giovanni PutotoDoctors with Africa CUAMM, Padova, Italy.
Daniele TrevisanutoDepartment of Women and Children Health, University of Padova, Via Giustiniani, 3, 35128, Padova, Italy. daniele.trevisanuto@unipd.it.ORCID http://orcid.org/0000-0002-6462-0079

Funding

Italian Agency for Development Cooperation AID 11497/CUAMM/MOZ
6 · The paper itself

Abstract

backgroundThermal control after birth is an essential part of neonatal care. However, the relationship between neonatal temperature at and after admission is unknown. This study aimed to evaluate the change between neonatal temperature at admission and at day 1, and its impact on mortality.

methodsRetrospective observational study at the Beira Central Hospital, Mozambique. Axillary temperatures were recorded at admission and at day 1 in 1,226 neonates who were admitted to the Special Care Unit between January 1 and December 31, 2017. The relationship between mortality rate and temperature change was evaluated with a matrix plot and a forest plot (obtained from a logistic regression model as odds ratios with 95% confidence intervals).

resultsNormothermia was found in 415 neonates (33.8%) at admission and in 638 neonates (52.0%) at day 1. Mortality rate was highest in (i) neonates who remained in severe/moderate hypothermia (74%), (ii) neonates who rewarmed from hypothermia (40-55%), and (iii) neonates who chilled to severe/moderate hypothermia (38-43%). Multivariable analysis confirmed that temperature change from admission to day 1 was an independent predictor of mortality (p < 0.0001).

conclusionsIn a low-resource setting, one out of three neonates was found hypothermic at day 1 irrespectively of admission temperature. Relevant thermal deviations occurred in a high proportion of newborns with normothermia at admission. Being cold at admission and becoming cold or hyperthermic at day 1 were associated with increased likelihood of mortality. Appropriate actions to prevent both hypothermia and hyperthermia represent both a challenge and a priority during postnatal period.

Indexed as

Infant MortalityBody TemperatureFemaleHumansHyperthermiaHypothermiaInfantInfant, Low Birth WeightInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleMozambiquePatient AdmissionPregnancyRetrospective StudiesBirthHypothermiaLow-resource settingMortalityTemperature

Identifiers

PMID33097025
PMCPMC7585226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.