Evidence map›Paper›PMID 33096836›Full record

ArticleMolecules (Basel, Switzerland)2020

Bio-Guided Isolation of Acetogenins from

Maria Teresa Gutiérrez, Alexandra G Durán, Francisco J R Mejías, José M G Molinillo, Diego Megias, Manuel M Valdivia, Francisco A Macías

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Acetogenins-Rich Fractions ofMolecules (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maria Teresa GutiérrezAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0003-2249-0496
Alexandra G DuránAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-9799-0850
Francisco J R MejíasAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0001-6952-2964
José M G MolinilloAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, 11510 Puerto Real, Spain.ORCID 0000-0002-7844-9401
Diego MegiasConfocal Microscopy Unit, Spanish National Cancer Research Center (CNIO), E-28029 Madrid, Spain.
Manuel M ValdiviaDepartment of Biomedicine, Biotechnology and Public Health, School of Science, Institute of Biomolecules (INBIO), University of Cadiz, 11510 Puerto Real, Spain.
Francisco A MacíasAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, 11510 Puerto Real, Spain.
Universidad de Cádiz · ESSpanish National Cancer Research Centre · ES

Funding

Ministerio de Ciencia y Tecnología AGL2017-88-083-R
6 · The paper itself

Abstract

Annonaceous acetogenins (ACGs) are lipophilic polyketides isolated exclusively from Annonaceae. They are considered to be amongst the most potent antitumor compounds. Nevertheless, their applications are limited by their poor solubility. The isolation of ACGs from

Indexed as

AcetogeninsAnnonaAntineoplastic Agents, PhytogenicBiological AvailabilityCell Line, TumorCell ProliferationCell SurvivalDrug CarriersDrug Screening Assays, AntitumorHEK293 CellsHumansMolecular StructureNanoparticlesPlant LeavesAcetogeninsAntineoplastic Agents, PhytogenicDrug CarriersacetogeninsAnnona cherimolaby-productscytotoxic activityencapsulationnutraceutical

Identifiers

PMID33096836
PMCPMC7587976
OpenAlexW3094243053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.