ArticleInternational journal of molecular sciences2020
Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains.
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Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
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Who cites it
25 citing papers in PubMed, 35 citations in OpenAlex.
- Comparative evaluation for small molecule somatostatin 4 receptor agonists:Frontiers in pharmacology · 2026Article
- Treadmill training or caloric restriction delays aging-associated increase in urocortin 2-induced hyperthermia in middle-aged male Wistar rats.Scientific reports · 2025Article
- Crosstalk Between Glycinergic and N-Methyl-D-Aspartate Receptor-Mediated Glutamatergic Transmission in Behaviours Associated with Opioid Use Disorder.International journal of molecular sciences · 2025Review
- Screening of candidate analgesics using a patient-derived human iPSC model of nociception identifies putative compounds for therapeutic treatment.Clinical and translational medicine · 2025Article
- Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025Review
- Allele-specific methylation of SSTR4 associated with aging and cognitive functions in patients with schizophrenia.PloS one · 2025Article
- Neuromedin U Neurons in the Edinger-Westphal Nucleus Respond to Alcohol Without Interfering with the Urocortin 1 Response.Neurochemical research · 2024Article
- Hemokinin-1 is a mediator of chronic restraint stress-induced pain.Scientific reports · 2023Article
- Aging Changes the Efficacy of Central Urocortin 2 to Induce Weight Loss in Rats.International journal of molecular sciences · 2023Article
- Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors.Brain sciences · 2023Review
- TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy.BMC biology · 2023Article
- The triple function of the capsaicin-sensitive sensory neurons: In memoriam János Szolcsányi.Temperature (Austin, Tex.) · 2023Review
- Development of Capsaicin-Containing Analgesic Silicone-Based Transdermal Patches.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Somatostatin Receptor 4 Agonism Normalizes Stress-Related Excessive Amygdala Glutamate Release and Pavlovian Aversion Learning and Memory in Rodents.Biological psychiatry global open science · 2022Article
- Descending control of nociception in insects?Proceedings. Biological sciences · 2022Review
- Exploration of Somatostatin Binding Mechanism to Somatostatin Receptor Subtype 4.International journal of molecular sciences · 2022Article
- Investigation of the Role of the TRPA1 Ion Channel in Conveying the Effect of Dimethyl Trisulfide on Vascular and Histological Changes in Serum-Transfer Arthritis.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro.International journal of molecular sciences · 2022Article
- Reassessment of SST4 Somatostatin Receptor Expression Using SST4-eGFP Knockin Mice and the Novel Rabbit Monoclonal Anti-Human SST4 Antibody 7H49L61.International journal of molecular sciences · 2021Article
- Human Somatostatin SSTInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Angéla KecskésDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.
Krisztina PohóczkyDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0003-0385-5162
Miklós KecskésCentre for Neuroscience, University of Pécs, H-7624 Pécs, Hungary.
Zoltán V VargaDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, H-1089 Budapest, Hungary.
Viktória KormosDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.
Éva SzőkeDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.
Nóra Henn-MikeCentre for Neuroscience, University of Pécs, H-7624 Pécs, Hungary.
Máté FehérDepartment of Neurosurgery, Kaposi Mór Teaching Hospital, H-7400 Kaposvár, Hungary.
József KunDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.
Attila GyeneseiBioinformatics Research Group, Genomics and Bioinformatics Core Facility, Szentágothai Research Centre University of Pécs, H-7624 Pécs, Hungary.
Éva RennerHuman Brain Tissue Bank, Semmelweis University, H-1089 Budapest, Hungary.
Miklós PalkovitsHuman Brain Tissue Bank, Semmelweis University, H-1089 Budapest, Hungary.
Péter FerdinandyDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, H-1089 Budapest, Hungary.
István M ÁbrahámCentre for Neuroscience, University of Pécs, H-7624 Pécs, Hungary.
Balázs GasznerCentre for Neuroscience, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0003-2830-2732
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, Molecular Pharmacology Research Group, University of Pécs, H-7624 Pécs, Hungary.
University of Pecs · HUSemmelweis University · HU
Funding
Developing Bioinformatics and Biostatistics competencies of European Biomedical Students, BECOMING 2019-1-HU01-KA203-061251EFOP 3.6.1-16-2016-0000EFOP 3.6.1.-16-2016-00004EFOP 3.6.2-16-2017-00008European Union's Horizon 2020 research and innovation programme under grant agreement 739593FEKUTSTRAT FIKPII-17886-4/23018GINOP 2.3.2-15-2016-00048GINOP 2.3.2-15-2016-00050GINOP 2.3.3-15-2016-00026GINOP 2.3.3-15-2016-00030Hungarian Brain Research Program 20017-1.2.1-NKP-2017-00002, NAP2.0János Bolyai Research Scholarship of the Hungarian Academy of Sciences János Bolyai Research Scholarship of the Hungarian Academy of SciencesNational Heart Program NVKP_16-1-2016-0017National Research, Development and Innovation Fund of Hungary NVKP_16New National Excellence Program of the Ministry of Human Capacities ÚNKP-19-3-I-SE-11NKFIH 112807NKFIH 124188University of Pécs, Medical School GYTK-KA-2020-01University of Pécs, Medical School KA-2019-12
Abstract
Somatostatin is an important mood and pain-regulating neuropeptide, which exerts analgesic, anti-inflammatory, and antidepressant effects via its Gi protein-coupled receptor subtype 4 (SST
Indexed as
AffectAnalgesicsAnimalsBrainButanesCHO CellsCricetulusElectrophysiologyHumansMaleMice, Inbred C57BLMice, Mutant StrainsMolecular Targeted TherapyNaphthalenesNeuronsReceptors, Somatostatin(1'S, 2S)-4-amino-N-(1'-carbamoyl-2'-phenylethyl)-2-(4''-methyl-1''-naphthalenesulfonylamino)butanamideAnalgesicsButanesNaphthalenesReceptors, SomatostatinSLC17A7 protein, humansomatostatin receptor subtype-4SulfonesVesicular Glutamate Transport Protein 1M-currentmood regulationpainRNA scope in situ hybridizationsomatosensory cortexSST4 receptorβ-galactosidase immunohistochemistry
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.