Evidence map›Paper›PMID 33096723›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Betaine and Isoquinoline Alkaloids Protect against Heat Stress and Colonic Permeability in Growing Pigs.

Hieu Huu Le, Majid Shakeri, Hafiz Ansar Rasul Suleria, Weicheng Zhao, Rachel Mai McQuade, Deborah Jayne Phillips, Eva Vidacs, John Barton Furness, Frank Rowland Dunshea, Valeria Artuso-Ponte and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Research progress on anti-stress nutrition strategies in swine.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Review
  10. Article
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Hieu Huu LeFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0001-8649-6892
Majid ShakeriFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Hafiz Ansar Rasul SuleriaFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-2450-0830
Weicheng ZhaoFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Rachel Mai McQuadeFlorey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia.
Deborah Jayne PhillipsFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Eva VidacsFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
John Barton FurnessFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-0219-3438
Frank Rowland DunsheaFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-3998-1240
Valeria Artuso-PontePhytobiotics Futterzusatzstoffe GmbH, D-65343 Eltville, Germany.
Jeremy James CottrellFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-1899-2090
The University of Melbourne · AUMorphoSys (Germany) · DEUniversity of Leeds · GB

Funding

AUSTRALIAN PORK LIMITED 2018/0076Phytobiotics Futterzusatzstoffe GmbH, D-65343 Eltville, Germany Sangrovit
6 · The paper itself

Abstract

Heat stress (HS) compromises productivity of pork production, in part as a result of increased oxidative stress and inflammatory responses, particularly within the gastrointestinal tract. This study aimed to investigate whether plant-derived betaine and isoquinoline alkaloids could ameliorate HS in pigs. Fifty female Large White × Landrace grower pigs, which were acclimated to control (CON), control plus betaine (BET), or control plus isoquinoline alkaloids (IQA) diets for 14 days were then exposed to heat stress or thermoneutral condition. Both BET and IQA partially ameliorated increases in respiration rate (

Indexed as

alkaloidsantioxidantsbetainegut healthheat stresspermeabilitythermoregulation

Identifiers

PMID33096723
PMCPMC7589639
OpenAlexW3094547752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.