ArticleJournal of clinical medicine2020
Stressful Life Events and the Clinical Expression of Obsessive-Compulsive Disorder (OCD): An Exploratory Study.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Cognitive Training via a Mobile Application to Reduce Obsessive-Compulsive-Related Distress and Cognitions During the COVID-19 Outbreaks: A Randomized Controlled Trial Using a Subclinical Cohort.Behavior therapy · 2022Trial
- "It Doesn't Matter Where OCD Comes From," or Does It?Current psychiatry reports · 2026Review
- Obsessive-Compulsive Disorder in three understudied populations: A review of Latino, Black, and Sexual & Gender Minority Individuals.Current psychiatry reports · 2026Review
- Network analysis of anxiety, depression, stress, and sleep disturbances in healthcare workers.Frontiers in psychiatry · 2026Article
- Psychometric Evaluation of the Over-Cleanliness Scale (OCS) Amid Covid-19 Pandemic and the Role of Perceived Stress and OCD Proneness on Over-Cleanliness: A Cross-Sectional Study.Health science reports · 2025Article
- Biological, Psychosocial, and Microbial Determinants of Childhood-Onset Obsessive-Compulsive Disorder: A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Concurrent Occurrence of Obsessive-Compulsive Disorder and Myofascial Pain Dysfunction Syndrome: A Case Series.Frontiers in dentistry · 2025Article
- The Role of Epigenetics in the Pathogenesis and Potential Treatment of Obsessive-compulsive Disorder.Current neuropharmacology · 2025Review
- Silent Infections are not So Silent: The Emerging Role of Combined Infections, Inflammation, and Vitamin Levels in OCD.Clinical neuropsychiatry · 2024Article
- The perceived long-term impact of COVID-19 on OCD symptomology.Journal of obsessive-compulsive and related disorders · 2023Article
- Genetic influences on the interplay between obsessive-compulsive behavior symptoms and cannabis use during adolescence.Journal of adolescence · 2023Article
- Investigating the correlation between perceived stress and health anxiety with obsessive-compulsive disorder and quality of life during COVID-19 pandemic.BMC psychology · 2023Article
- Impact of the COVID-19 pandemic on obsessive-compulsive symptoms in the Swiss general population.Frontiers in psychology · 2023Article
- SAPAP3, SPRED2, and obsessive-compulsive disorder: the search for fundamental phenotypes.Frontiers in molecular neuroscience · 2023Article
- The impact of the coronavirus pandemic on specific symptom dimensions and severity in OCD: A comparison before and during COVID-19 in the context of stress responses.Journal of obsessive-compulsive and related disorders · 2021Article
- Stress Influences the Effect of Obsessive-Compulsive Symptoms on Emotion Regulation.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundIn obsessive-compulsive disorder (OCD), symptom content and severity appear to fluctuate over the course of the life cycle in accordance with stressful life events. The objective of this paper was to compare OCD patients with and without reported stressful life events (SLEs) in terms of the sociodemographics of patients and the clinical characteristics of OCD.
methodsThis was a cross-sectional study involving 1001 patients with OCD. Data concerning SLEs were collected via the Yale OCD Natural History Questionnaire, while for OCD symptoms, the Dimensional Yale-Brown Obsessive-Compulsive Scale was used.
resultsOf the 1001 OCD patients, 605 (60.5%) reported experiencing at least one SLE in their lifetime. Self-declared nonwhite skin color (odds ratio (OR) = 1.51), the presence of a sensory phenomenon (OR = 1.47), and comorbidity with post-traumatic stress disorder (PTSD) (OR = 2.38) were some of the logistic regression variables related to the reported SLEs with relevant statistical significance and risk (i.e., OR) values.
conclusionsOur results indicate that SLEs may make Brazilian OCD patients vulnerable to the onset or exacerbation of obsessive-compulsive symptoms. The positive association of the occurrence of SLEs and sensory phenomena in this population could corroborate that environmental influences impact the neurobiology associated with OCD, and likely with other psychiatric disorders as well.
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