Evidence map›Paper›PMID 33096703›Full record

ReviewMicroorganisms2020

Rhinovirus Infection in Children with Acute Bronchiolitis and Its Impact on Recurrent Wheezing and Asthma Development.

Carlotta Biagi, Alessandro Rocca, Giulia Poletti, Marianna Fabi, Marcello Lanari

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Decoding viral infections and risk for asthma: Biomarkers or clinical histories?Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  10. Article
  11. New Data on Anti-Inflammatory and Wound Healing Potential of TransgenicInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carlotta BiagiDepartment of Medical and Surgical Sciences, Pediatric Emergency Unit, St Orsola Polyclinic, University of Bologna, 40138 Bologna, Italy.
Alessandro RoccaDepartment of Medical and Surgical Sciences, Pediatric Emergency Unit, St Orsola Polyclinic, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-3406-630X
Giulia PolettiDepartment of Medical and Surgical Sciences, Pediatric Emergency Unit, St Orsola Polyclinic, University of Bologna, 40138 Bologna, Italy.
Marianna FabiDepartment of Medical and Surgical Sciences, Pediatric Emergency Unit, St Orsola Polyclinic, University of Bologna, 40138 Bologna, Italy.
Marcello LanariDepartment of Medical and Surgical Sciences, Pediatric Emergency Unit, St Orsola Polyclinic, University of Bologna, 40138 Bologna, Italy.
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute bronchiolitis represents the leading cause of hospitalization in infants. Together with a respiratory syncytial virus, rhinovirus (RV) is one of the most common pathogens associated with bronchiolitis, and its genetic diversity (>150 types) makes the recurrence of RV infections each year quite typical. The frequency of RV infection and co-infection with other viruses and its impact on the clinical course of bronchiolitis have been studied by several authors with controversial results. Some studies demonstrate that multiple virus infections result in more severe clinical presentation and a higher risk of complications, whereas other studies suggest no influence on clinical course. Moreover, RV bronchiolitis has been reported to potentially contribute to the development of long-term sequelae, such as recurrent wheezing and asthma, in the pediatric population. In the present review, we summarize the most recent findings of the role of RV infection in children with acute bronchiolitis, its impact on subsequent asthma development, and the implication in clinical practice.

Indexed as

asthmabronchiolitischildrenclinical severityrhinoviruswheezing

Identifiers

PMID33096703
PMCPMC7589781
OpenAlexW3093651312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.