Evidence map›Paper›PMID 33096678›Full record

ReviewJournal of clinical medicine2020

Clinical Application of Virtual Reality for Upper Limb Motor Rehabilitation in Stroke: Review of Technologies and Clinical Evidence.

Won-Seok Kim, Sungmin Cho, Jeonghun Ku, Yuhee Kim, Kiwon Lee, Han-Jeong Hwang, Nam-Jong Paik

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 95 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 7 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06999876 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia: A Double-blind, Sham-controlled, Randomized Controlled Study

TypeinterventionalSponsorNational University Health System, SingaporeRan2025 to 2026Enrolled90ConditionsStroke Patients With Hemiplegia or Hemiparesis in the Subacute StageArmsThe AscenZ-VIII Stimulator (Investigational Medical Device)
NCT07254676 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of Virtual Reality-Enhanced Rehabilitation on Upper Limb Recovery in Acute Post-Stroke Patients: a Pilot Study

TypeinterventionalSponsorUniversity Medical Centre MariborRan2022 to 2025Enrolled52ConditionsAcute Stroke Intervention, Rehabilitation ExerciseArmsVirtual Reality-enhanced rehabilitation, Conventional rehabilitation therapy (CRT)
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 7 syntheses or guidelines pooled it, 218 citations in OpenAlex.

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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Won-Seok KimDepartment of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do 13620, Korea.ORCID 0000-0002-1199-5707
Sungmin ChoDelvine Inc., Seoul 08788, Korea.ORCID 0000-0002-2421-5116
Jeonghun KuDepartment of Biomedical Engineering, College of Medicine, Keimyung University, Daegu 42601, Korea.ORCID 0000-0002-9610-0078
Yuhee KimYbrain Research Institute, Seongnam-si, Gyeonggi-do 13449, Korea.
Kiwon LeeYbrain Research Institute, Seongnam-si, Gyeonggi-do 13449, Korea.
Han-Jeong HwangDepartment of Electronics and Information, Korea University, Sejong 30019, Korea.ORCID 0000-0002-1183-1219
Nam-Jong PaikDepartment of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do 13620, Korea.ORCID 0000-0002-5193-8678
Seoul National University Bundang Hospital · KRKeimyung University · KRKorea University · KR

Funding

Ministry of Trade Industry and Energy (Korea), Ministry of Science and Information and Communications Technology (Korea), and the Ministry of Health and Welfare (Korea) under the Technology Development Program for AI-Bio-Robot-Medicine Convergence 20001650Seoul National University Bundang Hospital (SNUBH) Research Fund 02-2016-032
6 · The paper itself

Abstract

Neurorehabilitation for stroke is important for upper limb motor recovery. Conventional rehabilitation such as occupational therapy has been used, but novel technologies are expected to open new opportunities for better recovery. Virtual reality (VR) is a technology with a set of informatics that provides interactive environments to patients. VR can enhance neuroplasticity and recovery after a stroke by providing more intensive, repetitive, and engaging training due to several advantages, including: (1) tasks with various difficulty levels for rehabilitation, (2) augmented real-time feedback, (3) more immersive and engaging experiences, (4) more standardized rehabilitation, and (5) safe simulation of real-world activities of daily living. In this comprehensive narrative review of the application of VR in motor rehabilitation after stroke, mainly for the upper limbs, we cover: (1) the technologies used in VR rehabilitation, including sensors; (2) the clinical application of and evidence for VR in stroke rehabilitation; and (3) considerations for VR application in stroke rehabilitation. Meta-analyses for upper limb VR rehabilitation after stroke were identified by an online search of Ovid-MEDLINE, Ovid-EMBASE, the Cochrane Library, and KoreaMed. We expect that this review will provide insights into successful clinical applications or trials of VR for motor rehabilitation after stroke.

Indexed as

hemiplegianeuronal plasticityrecovery of functionrehabilitationsensorstrokevirtual reality

Identifiers

PMID33096678
PMCPMC7590210
OpenAlexW3094417548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.