Evidence map›Paper›PMID 33096221›Full record

ArticlePharmacological research2021

Naringenin is a powerful inhibitor of SARS-CoV-2 infection in vitro.

Nicola Clementi, Carolina Scagnolari, Antonella D'Amore, Fioretta Palombi, Elena Criscuolo, Federica Frasca, Alessandra Pierangeli, Nicasio Mancini, Guido Antonelli, Massimo Clementi and 2 more

Abstract readLetterComment
In one paragraph

Article in Pharmacological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Review
  6. Metabolic engineering ofMetabolic engineering communications · 2024
    Article
  7. Review
  8. In vitro study on efficacy of SKF7BMC complementary medicine and therapies · 2024
    Article
  9. Review
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  11. Article
  12. Article
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  18. Conformational rearrangements in the second voltage sensor domain switch PIPProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Nicola ClementiLaboratory of Medical Microbiology and Virology at "Vita-Salute" San Raffaele University, Milan, 20132 Italy; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, 20132 Italy.
Carolina ScagnolariLaboratory of Virology, Department of Molecular Medicine, Istituto Pasteur Italia, SAPIENZA University of Rome, Rome, Italy.
Antonella D'AmoreUnit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, 16 Via A. Scarpa, Rome, 00161 Italy.
Fioretta PalombiUnit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, 16 Via A. Scarpa, Rome, 00161 Italy.
Elena CriscuoloLaboratory of Medical Microbiology and Virology at "Vita-Salute" San Raffaele University, Milan, 20132 Italy.
Federica FrascaLaboratory of Virology, Department of Molecular Medicine, Istituto Pasteur Italia, SAPIENZA University of Rome, Rome, Italy.
Alessandra PierangeliLaboratory of Virology, Department of Molecular Medicine, Istituto Pasteur Italia, SAPIENZA University of Rome, Rome, Italy.
Nicasio ManciniLaboratory of Medical Microbiology and Virology at "Vita-Salute" San Raffaele University, Milan, 20132 Italy; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, 20132, Italy.
Guido AntonelliLaboratory of Virology, Department of Molecular Medicine, Istituto Pasteur Italia, SAPIENZA University of Rome, Rome, Italy.
Massimo ClementiLaboratory of Medical Microbiology and Virology at "Vita-Salute" San Raffaele University, Milan, 20132 Italy; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Hospital, Milan, 20132 Italy.
Armando CarpanetoDepartment of Earth, Environment and Life Sciences (DISTAV) - University of Genoa, Viale Benedetto XV 5, Genova, 16132 Italy; Institute of Biophysics, National Research Council, Via De Marini 6, Genoa, 16149 Italy.
Antonio FilippiniUnit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, 16 Via A. Scarpa, Rome, 00161 Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19FlavanonesPharmaceutical PreparationsHumansSARS-CoV-2FlavanonesnaringeninPharmaceutical Preparations

Identifiers

PMID33096221
PMCPMC7574776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.