Evidence map›Paper›PMID 33096086›Full record

ArticleJournal of hepatology2021

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points.

Marcos F Fondevila, Maria Mercado-Gómez, Amaia Rodríguez, Maria J Gonzalez-Rellan, Paula Iruzubieta, Víctor Valentí, Javier Escalada, Markus Schwaninger, Vincent Prevot, Carlos Dieguez and 4 more

Abstract readLetterComment
In one paragraph

Article in Journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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  8. SARS-CoV-2 receptor ACE2 is upregulated by fatty acids in human MASH.JHEP reports : innovation in hepatology · 2024
    Article
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  12. COVID-19 and the liver: Are footprints still there?World journal of gastroenterology · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Marcos F FondevilaDepartment of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain.
Maria Mercado-GómezLiver Disease Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, and CIBER de Enfermedades Hepaticas y Digestivas (CIBERehd), Spain.
Amaia RodríguezCIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain; Obesity Area, Clínica Universidad de Navarra and IdiSNA, Pamplona, Spain.
Maria J Gonzalez-RellanDepartment of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain.
Paula IruzubietaDepartment of Gastroenterology and Hepatology, Marqués de Valdecilla University Hospital, Research Institute Marqués de Valdecilla (IDIVAL), Santander, Spain.
Víctor ValentíCIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain; Obesity Area, Clínica Universidad de Navarra and IdiSNA, Pamplona, Spain.
Javier EscaladaCIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain; Obesity Area, Clínica Universidad de Navarra and IdiSNA, Pamplona, Spain.
Markus SchwaningerInstitute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany.
Vincent PrevotUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, UMR-S 1172, European Genomic Institute for Diabetes (EGID), F-59000 Lille, France.
Carlos DieguezDepartment of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain.
Javier CrespoDepartment of Gastroenterology and Hepatology, Marqués de Valdecilla University Hospital, Research Institute Marqués de Valdecilla (IDIVAL), Santander, Spain.
Gema FrühbeckCIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain; Obesity Area, Clínica Universidad de Navarra and IdiSNA, Pamplona, Spain.
Maria L Martinez-ChantarLiver Disease Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160 Derio, and CIBER de Enfermedades Hepaticas y Digestivas (CIBERehd), Spain. Electronic address: mlmartinez@cicbiogune.es.
Ruben NogueirasDepartment of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), Spain; Galician Agency of Innovation (GAIN), Santiago de Compostela, Spain. Electronic address: ruben.nogueiras@usc.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Non-alcoholic Fatty Liver DiseaseHumansObesityRetrospective StudiesSARS-CoV-2Virus Internalization

Identifiers

PMID33096086
PMCPMC7574841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.