Evidence map›Paper›PMID 33095801›Full record

ArticlePloS one2020

The impact of lockdown enforcement during the SARSCoV-2 pandemic on the timing of presentation and early outcomes of patients with ST-elevation myocardial infarction.

Ofer Kobo, Roi Efraim, Majdi Saada, Natalia Kofman, Ala Abu Dogosh, Yigal Abramowitz, Doron Aronson, Sa'ar Minha, Ariel Roguin, Simcha R Meisel

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  5. The effect of COVID-19 pandemic on admission, management and mortality of pulmonary embolism in cancer patients.International journal of cardiology. Cardiovascular risk and prevention · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ofer KoboDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel.ORCID 0000-0001-7418-498X
Roi EfraimDepartment of Cardiology, Rambam Health Care Campus, Haifa, Israel.
Majdi SaadaDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel.
Natalia KofmanDepartment of Cardiology, Shamir Medical Center, Zerifin, Israel.
Ala Abu DogoshDepartment of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.
Yigal AbramowitzDepartment of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.
Doron AronsonDepartment of Cardiology, Rambam Health Care Campus, Haifa, Israel.
Sa'ar MinhaDepartment of Cardiology, Shamir Medical Center, Zerifin, Israel.
Ariel RoguinDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel.
Simcha R MeiselDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel.
Technion – Israel Institute of Technology · ILBen-Gurion University of the Negev · ILHillel Yaffe Medical Center · ILTel Aviv University · ILRambam Health Care Campus · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEarly reports described decreased admissions for acute cardiovascular events during the SarsCoV-2 pandemic. We aimed to explore whether the lockdown enforced during the SARSCoV-2 pandemic in Israel impacted the characteristics of presentation, reperfusion times, and early outcomes of ST-elevation myocardial infarction (STEMI) patients.

methodsA multicenter prospective cohort comprising all STEMI patients treated by primary percutaneous coronary intervention admitted to four high-volume cardiac centers in Israel during lockdown (20/3/2020-30/4/2020). STEMI patients treated during the same period in 2019 served as controls.

resultsThe study comprised 243 patients, 107 during the lockdown period of 2020 and 136 during the same period in 2019, with no difference in demographics and clinical characteristics. Patients admitted in 2020 had higher admission and peak troponin levels, had a 2.4 fold greater likelihood of Door-to-balloon times> 90 min (95%CI: 1.2-4.9, p = 0.01) and 3.3 fold greater likelihood of pain-to-balloon times> 12 hours (OR 3.3, 95%CI: 1.3-8.1, p<0.01). They experienced higher rates hemodynamic instability (25.2% vs 14.7%, p = 0.04), longer hospital stay (median, IQR [4, 3-6 Vs 5, 4-6, p = 0.03]), and fewer early (<72 hours) discharge (12.4% Vs 32.4%, p<0.001).

conclusionsThe lockdown imposed during the SARSCoV-2 pandemic was associated with a significant lag in the time to reperfusion of STEMI patients. Measures to improves this metric should be implemented during future lockdowns.

Indexed as

AgedCommunicable Disease ControlCOVID-19FemaleHumansIsraelLength of StayMaleMiddle AgedPandemicsPatient AdmissionPatient DischargePercutaneous Coronary InterventionProspective StudiesRegistriesSARS-CoV-2

Identifiers

PMID33095801
PMCPMC7584161
OpenAlexW3094545165

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.