Evidence map›Paper›PMID 33095699›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2021

2-D Ultrasonic Array-Based Optical Coherence Elastography.

Haochen Kang, Xuejun Qian, Ruimin Chen, Robert Wodnicki, Yizhe Sun, Runze Li, Yan Li, K Kirk Shung, Zhongping Chen, Qifa Zhou

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Bioengineering (Basel, Switzerland) · 2023
    Review
  6. Computational and structural biotechnology journal · 2023
    Review
  7. 2-D Array Design and Fabrication With Pitch-Shifting Interposer at Frequencies From 4 MHz up to 10 MHz.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  8. Biomedical optics express · 2022
    Article
  9. Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Haochen Kang
Xuejun Qian
Ruimin Chen
Robert Wodnicki
Yizhe Sun
Runze Li
Yan Li
K Kirk Shung
Zhongping Chen
Qifa Zhou
University of Southern California · USUniversity of California, Irvine · US

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
High-resolution Elastographic Assessment of the Optic Nerve HeadR01EY028662 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, SIGAL, IAN A · 2018 to 2021
$2.7M
High Resolution Elastograpy of Retina Under Prosthetic Electrical StimulationR01EY026091 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, ZHOU, QIFA · 2016 to 2019
$2.0M
Non-invasive Ultrasound Stimulated Retinal ProsthesisR01EY030126 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHOU, QIFA · 2019 to 2022
$2.0M
NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY026091NEI NIH HHS R01 EY028662NEI NIH HHS R01 EY030126
6 · The paper itself

Abstract

Acoustic radiation force optical coherence elastography (ARF-OCE) has been successfully implemented to characterize the biomechanical properties of soft tissues, such as the cornea and the retina, with high resolution using single-element ultrasonic transducers for ARF excitation. Most currently proposed OCE techniques, such as air puff and ARF, have less capability to control the spatiotemporal information of the induced region of deformation, resulting in limited accuracy and low temporal resolution of the shear wave elasticity imaging. In this study, we propose a new method called 2-D ultrasonic array-based OCE imaging, which combines the advantages of 3-D dynamic electronic steering of the 2-D ultrasonic array and high-resolution optical coherence tomography (OCT). The 3-D steering capability of the 2-D array was first validated using a hydrophone. Then, the combined 2-D ultrasonic array OCE system was calibrated using a homogenous phantom, followed by an experiment on ex vivo rabbit corneal tissue. The results demonstrate that our newly developed 2-D ultrasonic array-based OCE system has the capability to map tissue biomechanical properties accurately, and therefore, has the potential to be a vital diagnostic tool in ophthalmology.

Indexed as

Elasticity Imaging TechniquesAnimalsElasticityPhantoms, ImagingRabbitsTomography, Optical CoherenceUltrasonics

Identifiers

PMID33095699
PMCPMC8106462
OpenAlexW3094347233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.