ArticleMicrobial biotechnology2021
Detection of buried explosives with immobilized bacterial bioreporters.
Article in Microbial biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Design of bacterial DNT sensors based on computational models.Nucleic acids research · 2026Article
- Bioluminescent Microbial Bioreporters: A Personal Perspective.Biosensors · 2025Review
- An autonomous microbial sensor enables long-term detection of TNT explosive in natural soil.Nature communications · 2024Article
- A Microbial Cocaine Bioreporter.Sensors (Basel, Switzerland) · 2024Article
- Portable impedance-sensing device for microorganism characterization in the field.Scientific reports · 2023Article
- Performance upgrade of a microbial explosives' sensor strain by screening a high throughput saturation library of a transcriptional regulator.Computational and structural biotechnology journal · 2023Article
- Interpol review of the analysis and detection of explosives and explosives residues.Forensic science international. Synergy · 2023Review
- Design and engineering of genetically encoded protein biosensors for small molecules.Current opinion in biotechnology · 2022Review
- Review
- Introduction of quorum sensing elements into bacterial bioreporter circuits enhances explosives' detection capabilities.Engineering in life sciences · 2022Article
- Parallel engineering of environmental bacteria and performance over years under jungle-simulated conditions.PloS one · 2022Article
- Sense and sensibility: of synthetic biology and the redesign of bioreporter circuits.Microbial biotechnology · 2022Article
- Enhancing DNT Detection by a Bacterial Bioreporter: Directed Evolution of the Transcriptional Activator YhaJ.Frontiers in bioengineering and biotechnology · 2022Article
- Bacterial bioreporters for the detection of trace explosives: performance enhancement by DNA shuffling and random mutagenesis.Applied microbiology and biotechnology · 2021Article
- Detection of buried explosives with immobilized bacterial bioreporters.Microbial biotechnology · 2021Article
- Translating New Synthetic Biology Advances for Biosensing Into the Earth and Environmental Sciences.Frontiers in microbiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The unchecked dispersal of antipersonnel landmines since the late 19th century has resulted in large areas contaminated with these explosive devices, creating a substantial worldwide humanitarian safety risk. The main obstacle to safe and effective landmine removal is the identification of their exact location, an activity that currently requires entry of personnel into the minefields; to date, there is no commercialized technology for an efficient stand-off detection of buried landmines. In this article, we describe the optimization of a microbial sensor strain, genetically engineered for the remote detection of 2,4,6-trinitrotoloune (TNT)-based mines. This bioreporter, designed to bioluminescence in response to minute concentrations of either TNT or 2,4-dinitotoluene (DNT), was immobilized in hydrogel beads and optimized for dispersion over the minefield. Following modifications of the hydrogel matrix in which the sensor bacteria are encapsulated, as well as their genetic reporting elements, these sensor bacteria sensitively detected buried 2,4-dinitrotoluene in laboratory experiments. Encapsulated in 1.5 mm 2% alginate beads containing 1% polyacrylic acid, they also detected the location of a real metallic antipersonnel landmine under field conditions. To the best of our knowledge, this is the first report demonstrating the detection of a buried landmine with a luminescent microbial bioreporter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.