Evidence map›Paper›PMID 33095451›Full record

Observational studyAmerican journal of hematology2021

Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease.

Minke A E Rab, Celeste K Kanne, Jennifer Bos, Brigitte A van Oirschot, Camille Boisson, Maite E Houwing, Jorn Gerritsma, Erik Teske, Celine Renoux, Jurgen Riedl and 10 more

Abstract readLetterObservational Study
In one paragraph

Observational study in American journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Minke A E RabCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-8306-8726
Celeste K KanneDepartment of Pediatrics Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Jennifer BosCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Brigitte A van OirschotCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Camille BoissonLaboratory LIBM EA7424, University of Lyon 1, "Vascular Biology and Red Blood Cell" team, Lyon, France.
Maite E HouwingDepartment of Pediatric Hematology, Erasmus Medical Center, Rotterdam, The Netherlands.
Jorn GerritsmaEmma Children's Hospital, Pediatric Hematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Erik TeskeDepartment of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Celine RenouxLaboratory LIBM EA7424, University of Lyon 1, "Vascular Biology and Red Blood Cell" team, Lyon, France.
Jurgen RiedlResult Laboratory, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
Roger E G SchutgensVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Marije BartelsVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Erfan NurDepartment of Hematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Philippe JolyLaboratory LIBM EA7424, University of Lyon 1, "Vascular Biology and Red Blood Cell" team, Lyon, France.
Romain FortDepartment of Internal Medicine, Hospices Civils de Lyon, Lyon, France.
Marjon H CnossenDepartment of Pediatric Hematology, Erasmus Medical Center, Rotterdam, The Netherlands.
Richard van WijkCentral Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Philippe ConnesLaboratory LIBM EA7424, University of Lyon 1, "Vascular Biology and Red Blood Cell" team, Lyon, France.
Eduard J van BeersVan Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Vivien A SheehanDepartment of Pediatrics Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.ORCID 0000-0003-2837-2255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

VasoconstrictionAdolescentAnemia, Sickle CellBiomarkersChildChild, PreschoolFemaleHumansMaleOxygenBiomarkersOxygen

Identifiers

PMID33095451
PMCPMC7756395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.