Evidence map›Paper›PMID 33095433›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Tumor volume as a prognostic factor of locally advanced laryngeal cancer.

Natália Martins Magacho de Andrade, Rogério Aparecido Dedivitis, Daniel Marin Ramos, Leandro Luongo Matos, Marcio Ricardo Taveira Garcia, Gustavo Gonçalves Conti, Luiz Paulo Kowalski

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The Impact of Primary Tumor Volume on Survival of Patients with Non-Surgically Treated Advanced-Stage Hypopharyngeal Cancer- Retrospective Study and Literature Overview.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  2. Article
  3. Tumor Volume Staging Provides a Comparable Stratifying for Laryngeal Squamous Cell Cancer According to T Stages.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  4. Preoperative tracheotomy as reflection of tumor size impacting oncologic outcomes of patients with advanced stage glottic carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  5. Letter to the editor "Tumor volume as a prognostic factor of locally advanced laryngeal cancer".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Natália Martins Magacho de AndradeDepartment of Head and Neck Surgery, Instituto Central, University of Sao Paulo Medical School, 8° andar. Cerqueira César, São Paulo, 05403-000, Brazil. natmagacho@hotmail.com.ORCID http://orcid.org/0000-0002-3042-8855
Rogério Aparecido DedivitisDepartment of Head and Neck Surgery, Instituto Central, University of Sao Paulo Medical School, 8° andar. Cerqueira César, São Paulo, 05403-000, Brazil.
Daniel Marin RamosInstituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil.
Leandro Luongo MatosDepartment of Head and Neck Surgery, Instituto Central, University of Sao Paulo Medical School, 8° andar. Cerqueira César, São Paulo, 05403-000, Brazil.
Marcio Ricardo Taveira GarciaDepartment of Radiology, Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil.
Gustavo Gonçalves ContiDepartment of Radiology, Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil.
Luiz Paulo KowalskiDepartment of Head and Neck Surgery, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe TNM tumor staging system is the most widely used for laryngeal cancer. However, in the same T stage, lesions with different primary tumor volumes (TV) can be found, impacting treatment outcomes.

methods145 patients with T3 and T4a laryngeal cancer, according to Union for International Cancer Control, who underwent surgical treatment from 2008 to 2017, were analyzed. TV measurements were collected and compared to different outcomes.

resultsThe mean TV was 23.0 ± 16.4 cm

conclusionPrimary lesion TV showed significant association, in univariate analysis, with worse rates of recurrence and survival in advanced laryngeal cancer undergoing surgical treatment and can be a promising prognostic for these patients.

Indexed as

Laryngeal NeoplasmsDisease-Free SurvivalHumansNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRetrospective StudiesTumor BurdenImagingLaryngeal neoplasmsNeoplasm stagingPrognosisSurvivalThree-dimensional

Identifiers

PMID33095433

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.