Evidence map›Paper›PMID 33095373›Full record

ArticleResearch on child and adolescent psychopathology2021

Converging Multi-modal Evidence for Implicit Threat-Related Bias in Pediatric Anxiety Disorders.

Rany Abend, Mira A Bajaj, Chika Matsumoto, Marissa Yetter, Anita Harrewijn, Elise M Cardinale, Katharina Kircanski, Eli R Lebowitz, Wendy K Silverman, Yair Bar-Haim and 4 more

Abstract read
In one paragraph

Article in Research on child and adolescent psychopathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. The Cognitive-Affective Social Processing and Emotion Regulation (CASPER) model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Article
  3. Article
  4. The Organization of Anxiety Symptoms Along the Threat Imminence Continuum.Current topics in behavioral neurosciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Attentional biases in human anxiety.Neuroscience and biobehavioral reviews · 2022
    Review
  9. Article
  10. The prefrontal cortex, pathological anxiety, and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rany Abend *Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA. rany.abend@nih.gov.
Mira A Bajaj *Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Chika MatsumotoEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Marissa YetterEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Anita HarrewijnEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Elise M CardinaleEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Eli R LebowitzYale University, New Haven, CT, USA.
Wendy K SilvermanYale University, New Haven, CT, USA.
Yair Bar-HaimSchool of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel.
Amit LazarovSchool of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel.
Ellen LeibenluftEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Melissa BrotmanEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.
Daniel S PineEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bldg 15K, MSC-2670, Bethesda, MD, 20892, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Unit on Neuroscience and Novel TherapeuticsZIAMH002969 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BROTMAN, MELISSA · 2019 to 2025
$13.8M
Brain response associated with parent-based treatment for childhood anxiety disordersR61MH115113 · NIMH · YALE UNIVERSITY · PI GEE, DYLAN GRACE, LEBOWITZ, ELI · 2018 to 2019
$1.5M
Fibroblast Growth Factor 2's role in Fear and Approach Motivation in Anxious and Depressed Children and their MothersR21MH113946 · NIMH · YALE UNIVERSITY · PI LEBOWITZ, ELI, SILVERMAN, WENDY K. · 2017 to 2018
$461k
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIA MH002781NCATS NIH HHS UL1 TR001863NIMH NIH HHS R21 MH113946NIMH NIH HHS R61 MH115113
6 · The paper itself

Abstract

This report examines the relationship between pediatric anxiety disorders and implicit bias evoked by threats. To do so, the report uses two tasks that assess implicit bias to negative-valence faces, the first by eye-gaze and the second by measuring body-movement parameters. The report contrasts task performance in 51 treatment-seeking, medication-free pediatric patients with anxiety disorders and 36 healthy peers. Among these youth, 53 completed an eye-gaze task, 74 completed a body-movement task, and 40 completed both tasks. On the eye-gaze task, patients displayed longer gaze duration on negative relative to non-negative valence faces than healthy peers, F(1, 174) = 8.27, p = .005. In contrast, on the body-movement task, patients displayed a greater tendency to behaviorally avoid negative-valence faces than healthy peers, F(1, 72) = 4.68, p = .033. Finally, implicit bias measures on the two tasks were correlated, r(38) = .31, p = .049. In sum, we found an association between pediatric anxiety disorders and implicit threat bias on two tasks, one measuring eye-gaze and the other measuring whole-body movements. Converging evidence for implicit threat bias encourages future research using multiple tasks in anxiety.

Indexed as

Anxiety DisordersFearAdolescentAnxietyChildFixation, OcularHumansPrejudiceAnxietyAttentionAvoidanceBiasThreat

Identifiers

PMID33095373
PMCPMC7839316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.