ArticleInternational ophthalmology2021
Accuracy of the posterior corneal elevation values of Pentacam HR from different reference surfaces in early ectasia diagnosis.
Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Keratectasia severity staging and progression assessment based on the biomechanical E-staging.Eye and vision (London, England) · 2024Review
- Multi-modal imaging for the detection of early keratoconus: a narrative review.Eye and vision (London, England) · 2024Review
- Visual Corneal Photomechanical Analysis Is Combined with the Pentacam Correlation Index for the Diagnosis of Cone Corneas at Different Stages of Progression.Journal of healthcare engineering · 2022Article
- Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis.Frontiers in medicine · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDetecting the accuracy of various posterior elevation (PE) indices of Pentacam HR, and correlating them with some possibly related factors or parameters, in a cohort with early keratoconus (KC).
methodsA cross sectional study that was conducted at Eye World Hospital, Egypt. One hundred and two corneas were enrolled, including two groups; group 1 (50 corneas) having forme fruste or early KC, and group 2 (52 corneas) for healthy controls. Corneas were scanned using Pentacam HR (Oculus, Wetzlar, Germany). The investigated PE parameters were: PE from best fit sphere (BFS), PE from best fit toric ellipsoid (BFTE), PE from exclusion map of Belin Ambrosio's display (BAD), and PE from difference map of BAD. The four PE values were correlated to age, thinnest corneal thickness "TCT," posterior aberrations, and posterior Q value.
resultsAll the investigated indices were significantly different in group 1 compared to group 2 (p < 0.001). Accuracy of PE parameters revealed the highest AUROC for PE from BFTE (AUROC = 0.989, and best cutoff > 4 um with sensitivity 96.00% and specificity 96.15%). PE from difference map was the least accurate. Correlation coefficients showed a significant correlation between all the studied PE parameters and some of the posterior aberrations (root mean square of higher order aberrations, vertical coma, and spherical aberrations), besides a significant correlation with posterior Q value.
conclusionPE indices are sensitive detectors of early ectasia. PE from BFTE had the highest deduced AUROC. Alterations in PE values can significantly alter many posterior corneal aberrations and the posterior Q.
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