Evidence map›Paper›PMID 33094955›Full record

ArticleClinical and translational gastroenterology2020

Inflammatory Bowel Disease Reoperation Rate Has Decreased Over Time If Corrected by Prevalence.

Mafalda Santiago, Fernando Magro, Luís Correia, Francisco Portela, Paula Ministro, Paula Lago, Eunice Trindade, Cláudia Camila Dias

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Mafalda SantiagoCINTESIS-Center for Health Technology and Services Research, Porto, Portugal.
Fernando MagroGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Luís CorreiaGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Francisco PortelaGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Paula MinistroGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Paula LagoGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Eunice TrindadeGrupo de Estudo da Doença Inflamatória Intestinal (GEDII), Porto, Portugal.
Cláudia Camila DiasCINTESIS-Center for Health Technology and Services Research, Porto, Portugal.
Universidade do Porto · PTCentre for Health Technology and Services Research · PTCentro Hospitalar Tondela-Viseu · PTHospitais da Universidade de Coimbra · PTHospital de Santa Maria · PTHospital de Santo António · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the recent emergence of expensive biologic therapies, hospitalization and surgery remain important contributors for the overall costs of inflammatory bowel disease (IBD). In this study, we aimed to describe the burden of reoperations in patients with IBD by evaluating reoperation rates, charges, and risk factors over 16 years.

methodsWe performed a retrospective analysis of all hospital discharges, with focus on reoperations and with a primary diagnosis of IBD, in public hospitals between 2000 and 2015 in mainland Portugal from the Central Administration of the Health System's national registry. We collected data on patient, clinical, and healthcare charges. We used multivariate regressions to estimate the risk factors of IBD-related reoperations.

resultsWe found that 5% of IBD-related hospitalizations were related to reoperations. The number of reoperations per year increased by approximately 200%. However, when corrected by the prevalence of the disease, IBD reoperation rates decreased. Mean IBD-related charges per hospitalization were 7,780 &OV0556; in 2000 and 10,592 &OV0556; in 2015, with total charges reaching 6.7 million euros by the end of the study. Risk factors for reoperation include urgent hospitalization, in patients with ulcerative colitis (odds ratio 1.94, 95% confidence interval 1.19-3.17, P = 0.008), and colic disease, in patients with Crohn's disease (odds ratio 1.57, 95% confidence interval 1.06-2.34, P = 0.025). DISCUSSION: To obtain an accurate scenario of reoperations among patients with IBD, it is mandatory to adjust the number of reoperations to the prevalence of the disease. Reoperation and its risk factors should be closely monitored to decrease the burden of IBD to the healthcare system.

Indexed as

Cost of IllnessAdultAgedColitis, UlcerativeCrohn DiseaseFemaleHealth Care CostsHospitalizationHumansMaleMiddle AgedOdds RatioPortugalPrevalenceReoperationRetrospective Studies

Identifiers

PMID33094955
PMCPMC7494150
OpenAlexW3094552386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.