ArticleMovement disorders : official journal of the Movement Disorder Society2021
Stress and Mindfulness in Parkinson's Disease: Clinical Effects and Potential Underlying Mechanisms.
Article in Movement disorders : official journal of the Movement Disorder Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05779137 (The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Mindfulness-based Cognitive Therapy on Psychological Distress in People With Parkinson's Disease
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- The efficacy of psychological interventions for anxiety in Parkinson's disease: a systematic review and meta-analysis including mindfulness and mind-body approaches.BMC psychology · 2026Pooled it
- Trial
- Lifestyle medicine for neuroprotection: evidence and implementation in Asian contexts.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Stress and Parkinson's disease: from dysfunctional detection to impaired handling: a narrative review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Not always the usual suspect: symptom variations in Parkinson's disease beyond ON-OFF fluctuations.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Mindfulness combined with cognitive motor dual task training in Parkinson's disease with mild cognitive impairment.iScience · 2026Article
- Relationships between perceived social support, self-efficacy, coping styles and resilience in older patients with Parkinson's disease.BMC geriatrics · 2026Article
- From Stress to Neurodegeneration: A New Look at the Pathogenesis of Parkinson's Disease.Biomedicines · 2026Review
- Article
- A Holistic Wellness Prescription for Parkinson's Disease: Evidence-Based Perspectives and Unmet Needs.Movement disorders clinical practice · 2026Review
- Neuropsychiatric, stress-related symptoms and essential tremor clinical variability.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Lifestyle medicine in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- The effects of war on patients with Parkinson's disease.Clinical parkinsonism & related disorders · 2026Article
- The interplay between stress, inflammation and Parkinson's disease: insights from the COVID-19 pandemic.NPJ Parkinson's disease · 2025Article
- Review of the Effects of Lifestyle Modification on Parkinson's Disease.American journal of lifestyle medicine · 2025Article
- DRN-SNc serotonergic circuit drives stress-induced motor deficits and Parkinson's disease vulnerability.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Systematic review of wearables assessing medication effect on motor function and symptoms in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Review
- Unleashing creativity in people with Parkinson's disease: a pilot study of a co-designed creative arts therapy.Journal of neurology · 2025Article
- Psychiatric Disorders and Cognitive Fluctuations in Parkinson's Disease: Changing Approaches in the First Decades of the 21st Century.Brain sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with Parkinson's disease (PD) are very vulnerable to the negative effects of psychological distress: neuropsychiatric symptoms, such as anxiety and depression, are highly prevalent in PD; motor symptoms (such as tremor) typically worsen in stressful situations; and dopaminergic medication is less effective. Furthermore, animal studies of PD suggest that chronic stress may accelerate disease progression. Adequate self-management strategies are therefore essential to reduce the detrimental effects of chronic stress on PD. Mindfulness-based interventions encourage individuals to independently self-manage and adapt to the challenges created by their condition. In PD, emerging clinical evidence suggests that mindfulness-based interventions may reduce psychological distress and improve clinical symptoms, but insight into the underlying mechanisms is lacking. In this viewpoint, we provide a systematic overview of existing mindfulness trials in PD. Furthermore, we discuss the cerebral mechanisms involved in acute and chronic stress, and the impact of mindfulness-based interventions on these networks. In addition, we delineate a hypothetical mechanistic framework of how chronic stress may increase the susceptibility for neuropsychiatric symptoms in PD and may potentially even influence disease progression. We end with offering recommendations for future research. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.