Evidence map›Paper›PMID 33094697›Full record

ArticleToxicology and industrial health2020

Rare cases of severe life-threatening lead poisoning due to accident or chronic occupational exposure to lead and manganese: Diagnosis, treatment, and prognosis.

Xuqin Du, Wei Zheng, Qiao Ye

Open access · greenAbstract readCase Reports
In one paragraph

Article in Toxicology and industrial health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Effect of Pb-exposure and B vitamin deficiencies on δ-aminolevulinic acid dehydratase activity among workers from Pb recycling plants.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Xuqin DuDepartment of Occupational Medicine and Toxicology, 74639Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0714-423X
Wei Zheng138262School of Health Sciences, Purdue University, West Lafayette, Indiana, USA.
Qiao YeDepartment of Occupational Medicine and Toxicology, 74639Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNPurdue University West Lafayette · US

Funding

Lead Exposure and Beta-Amyloid Transport by Brain BarriersR01ES027078 · NIEHS · PURDUE UNIVERSITY · PI DU, YANSHENG, ZHENG, WEI · 2017 to 2021
$2.2M
The Pathogenic Role of Pb in Cerebral Amyloid Angiopathy and AD SupplementR21AG067923 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI DU, YANSHENG, TERRITO, PAUL RICHARD · 2020 to 2022
$642k
NIA NIH HHS R21 AG067923NIEHS NIH HHS R01 ES027078
6 · The paper itself

Abstract

backgroundChronic long-term, low-dose environmental and occupational exposure to lead (Pb) has been extensively studied in large cohorts worldwide among general populations, miners, smelters, or battery workers. However, studies on severe life-threatening Pb poisoning due to accidental or chronic occupational exposure to Pb and manganese (Mn) were rarely reported.

methodsWe present one case of acute severe Pb poisoning and compare it with another severe chronic occupational exposure case involving Pb and Mn. A 27-year-old woman mistakenly took a large quantity of pure Pb powder as an herbal remedy; she developed abdominal colic, severe nausea, vomiting, fatigue, and cutaneous and sclera icterus. Laboratory tests showed her blood lead level (BLL) of 173.5 µg dL

conclusionClinical manifestations of acute and chronic severe Pb poisoning are different. Chelation therapy with CaNa

Indexed as

AdultChelation TherapyDose-Response Relationship, DrugFemaleHumansLeadLead PoisoningMaleManganeseMiddle AgedOccupational ExposurePlant PreparationsPrognosisTime FactorsLeadManganesePlant PreparationsAcutechronicco-exposurelead poisoningliver injurymanganese

Identifiers

PMID33094697
PMCPMC7752850
OpenAlexW3094207140

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.