Evidence map›Paper›PMID 33094522›Full record

ArticleClinical cardiology2020

Risk factors and electrocardiogram characteristics for mortality in critical inpatients with COVID-19.

Lingzhi Li, Shudi Zhang, Bing He, Xiaobei Chen, Shihong Wang, Qingyan Zhao

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  9. Meta-analysis and systematic literature review of COVID-19 associated bradycardia as a predictor of mortality.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Review
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  12. Mortality risk in COVID-19 patients with right bundle branch block.Revista espanola de cardiologia (English ed.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lingzhi LiDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Shudi ZhangDepartment of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Bing HeDepartment of Pediatrics, Renmin Hospital of Wuhan University, Wuhan, China.
Xiaobei ChenDepartment of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China.
Shihong WangDepartment of Pediatrics, Renmin Hospital of Wuhan University, Wuhan, China.
Qingyan ZhaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0002-9610-2452
Wuhan University · CN

Funding

National Natural Science Foundation of China 81670303 and 81970277
6 · The paper itself

Abstract

backgroundThe novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. HYPOTHESIS: The possible risk factors that lead to death in critical inpatients with coronavirus disease 2019 (COVID-19) are not yet fully understood.

methodsIn this single-center, retrospective study, we enrolled 113 critical patients with COVID-19 from Renmin Hospital of Wuhan University between February 1, 2020 and March 15, 2020. Patients who survived or died were compared.

resultsA total of 113 critical patients with COVID-19 were recruited; 50 (44.3%) died, and 63 (55.7%) recovered. The proportion of patients with ventricular arrhythmia was higher in the death group than in the recovery group (P = .021) and was higher among patients with myocardial damage than patients without myocardial damage (P = .013). Multivariate analysis confirmed independent predictors of mortality from COVID-19: age > 70 years (HR 1.84, 95% CI 1.03-3.28), initial neutrophil count over 6.5 × 10

conclusionsOld age (>70 years), neutrophilia, C-reactive protein greater than 100 mg/L and lactate dehydrogenase over 300 U/L are high-risk factors for mortality in critical patients with COVID-19. Sinus tachycardia and ventricular arrhythmia are independent ECG risk factors for mortality from COVID-19.

Indexed as

AdultAgedCOVID-19C-Reactive ProteinCritical IllnessElectrocardiographyFemaleHumansInpatientsLeukocyte CountMaleMiddle AgedNeutrophilsRetrospective StudiesRisk FactorsSeverity of Illness IndexC-Reactive ProteinarrhythmiaCOVID-19critical typemortalityrisk factors

Identifiers

PMID33094522
PMCPMC7724237
OpenAlexW3093802981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.