Hypocalcemia: the quest for the cause of a major biochemical feature of COVID-19.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

1. The effect of low serum calcium level on the severity and mortality of Covid patients: A systematic review and meta-analysis.Immunity, inflammation and disease · 2021
   Pooled it
2. The link between COVID-19 and VItamin D (VIVID): A systematic review and meta-analysis.Metabolism: clinical and experimental · 2021
   Pooled it
3. COVID-19-Induced Refractory Symptomatic Hypocalcemia in a Patient With Parathyroid Gland Reimplantation.Case reports in endocrinology · 2024
   Article
4. Calcium, Phosphorus and Magnesium Abnormalities Associated with COVID-19 Infection, and Beyond.Biomedicines · 2023
   Review
5. Low vitamin D levels predict outcomes of COVID-19 in patients with both severe and non-severe disease at hospitalization.Endocrine · 2023
   Article
6. The osteo-metabolic phenotype of COVID-19: an update.Endocrine · 2022
   Review
7. Vertebral fractures at hospitalization predict impaired respiratory function during follow-up of COVID-19 survivors.Endocrine · 2022
   Article
8. Hypocalcemia in COVID-19: Prevalence, clinical significance and therapeutic implications.Reviews in endocrine & metabolic disorders · 2022
   Review
9. Revisiting the endocrine and metabolic manifestations of COVID-19 two years into the pandemic.Reviews in endocrine & metabolic disorders · 2022
   Review
10. Lower plasma calcium associated with COVID-19, but not with disease severity: a two-centre retrospective cohort study.Infectious diseases (London, England) · 2022
    Article
11. Calcium Signals during SARS-CoV-2 Infection: Assessing the Potential of Emerging Therapies.Cells · 2022
    Review
12. Vitamin D: Dosing, levels, form, and route of administration: Does one approach fit all?Reviews in endocrine & metabolic disorders · 2021
    Review
13. Hypocalcemia in COVID-19 is associated with low vitamin D levels and impaired compensatory PTH response.Endocrine · 2021
    Article
14. Serum Calcium and Vitamin D levels: Correlation with severity of COVID-19 in hospitalized patients in Royal Hospital, Oman.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Observational
15. Serum Zinc, Copper, and Other Biometals Are Associated with COVID-19 Severity Markers.Metabolites · 2021
    Article
16. Hypovitaminosis D and the endocrine phenotype of COVID-19.Endocrine · 2021
    Review
17. Hypocalcemia is a distinctive biochemical feature of hospitalized COVID-19 patients.Endocrine · 2021
    Article
18. Conflicts over calcium and the treatment of COVID-19.Evolution, medicine, and public health · 2021
    Review
19. High Prevalence of Hypocalcemia in Non-severe COVID-19 Patients: A Retrospective Case-Control Study.Frontiers in medicine · 2020
    Article

Corrections and comments

• Comment on
  Mechanistic basis and therapeutic relevance of hypocalcemia during severe COVID-19 infection.2020

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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