Evidence map›Paper›PMID 33094429›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Transcranial magnetic resonance-guided focused ultrasound thalamotomy as a safe treatment option in multiple sclerosis patients with essential tremor.

Cesare Gagliardo, Paolo Ragonese, Gerardo Domenico Iacopino, Giuseppe Salemi, Massimo Midiri, Marco D'Amelio

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Clinical application of magnetic resonance-guided focused ultrasound in Parkinson's disease: a meta-analysis of randomized clinical trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
  2. Article
  3. Surgical Advances in Parkinson's Disease.Current neuropharmacology · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cesare Gagliardo *Department of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Radiological Sciences, University of Palermo, Via del Vespro, 129, 90127, Palermo, PA, Italy. cesare.gagliardo@unipa.it.ORCID http://orcid.org/0000-0003-4088-2020
Paolo Ragonese *Department of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Neurology, Palermo, Italy.
Gerardo Domenico IacopinoDepartment of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Neurosurgery, Palermo, Italy.
Giuseppe SalemiDepartment of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Neurology, Palermo, Italy.
Massimo MidiriDepartment of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Radiological Sciences, University of Palermo, Via del Vespro, 129, 90127, Palermo, PA, Italy.
Marco D'AmelioDepartment of Biomedicine, Neuroscience and Advanced Diagnostics-Section of Neurology, Palermo, Italy.
University of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial magnetic resonance-guided focused ultrasound is a recently introduced incisionless treating option for essential tremor and tremor-dominant idiopathic Parkinson disease. There is preliminary evidence that it may result in a promising effective treatment option for other movement disorders too. Here, we report on two patients with multiple sclerosis with medication refractory debilitating essential tremor comorbidity who successfully underwent unilateral Vim tcMRgFUS thalamotomy for tremor control. Patients' clinical condition and expanded disability status scale scores showed no changes during the 1-year follow-up period with no evidence of multiple sclerosis activity or progression.

Indexed as

Essential TremorMultiple SclerosisHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyThalamusTreatment OutcomeEssential TremorHigh-Intensity Focused Ultrasound AblationInterventional Magnetic Resonance ImagingMultiple SclerosisStereotaxic Techniques

Identifiers

PMID33094429
OpenAlexW3093553066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.