Evidence map›Paper›PMID 33094306›Full record

ArticleLab on a chip2020

Microfluidic devices powered by integrated elasto-magnetic pumps.

Jacob L Binsley, Elizabeth L Martin, Thomas O Myers, Stefano Pagliara, Feodor Y Ogrin

Erratum issuedAbstract read
In one paragraph

Article in Lab on a chip, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A frugal microfluidic pump.Lab on a chip · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jacob L BinsleyDepartment of Physics and Astronomy, University of Exeter, Physics Building, Stocker Road, Exeter, EX4 4QL, UK. jb778@exeter.ac.uk.ORCID 0000-0001-6957-6460
Elizabeth L MartinDepartment of Physics and Astronomy, University of Exeter, Physics Building, Stocker Road, Exeter, EX4 4QL, UK. jb778@exeter.ac.uk.ORCID 0000-0002-7796-740X
Thomas O MyersPlatform Kinetics Limited, Pegholme, Wharfebank Mills, Otley, LS21 3JP, UK.ORCID 0000-0002-2589-9839
Stefano PagliaraDepartment of Biosciences, University of Exeter, Living Systems Institute, Stocker Road, Exeter, EX4 4QD, UK.ORCID 0000-0001-9796-1956
Feodor Y OgrinDepartment of Physics and Astronomy, University of Exeter, Physics Building, Stocker Road, Exeter, EX4 4QL, UK. jb778@exeter.ac.uk.ORCID 0000-0002-9383-1473

Funding

Medical Research Council MC_PC_17189Medical Research Council MCPC17189Wellcome TrustWellcome Trust WT097835/Z/11/Z
6 · The paper itself

Abstract

We show how an asymmetric elasto-magnetic system provides a novel integrated pumping solution for lab-on-a-chip and point of care devices. This monolithic pumping solution, inspired by Purcell's 3-link swimmer, is integrated within a simple microfluidic device, bypassing the requirement of external connections. We experimentally prove that this system can provide tuneable fluid flow with a flow rate of up to 600 μL h-1. This fluid flow is achieved by actuating the pump using a weak, uniform, uniaxial, oscillating magnetic field, with field amplitudes in the range of 3-6 mT. Crucially, the fluid flow can be reversed by adjusting the driving frequency. We experimentally prove that this device can successfully operate on fluids with a range of viscosities, where pumping at higher viscosity correlates with a decreasing optimal driving frequency. The fluid flow produced by this device is understood here by examining the non-reciprocal motion of the elasto-magnetic component. This device has the capability to replace external pumping systems with a simple, integrated, lab-on-a-chip component.

Indexed as

Lab-On-A-Chip DevicesMicrofluidic Analytical TechniquesMagnetic PhenomenaMagneticsViscosity

Identifiers

PMID33094306
PMCPMC7654506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.