Evidence map›Paper›PMID 33094293›Full record

ArticleUnderstanding and interpreting machine learning in medical image computing applications : first international workshops, MLCN 2018, DLF 2018, and iMIMIC 2018, held in conjunction with MICCAI 2018, Granada, Spain, September 16-20, 2018 :...2018

Shortcomings of Ventricle Segmentation Using Deep Convolutional Networks.

Muhan Shao, Shuo Han, Aaron Carass, Xiang Li, Ari M Blitz, Jerry L Prince, Lotta M Ellingsen

Open access · greenAbstract read
In one paragraph

Article in Understanding and interpreting machine learning in medical image computing applications : first international workshops, MLCN 2018, DLF 2018, and iMIMIC 2018, held in conjunction with MICCAI 2018, Granada, Spain, September 16-20, 2018 :..., 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. ENRICHing medical imaging training sets enables more efficient machine learning.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  7. AUTOMATED VENTRICLE PARCELLATION AND EVAN'S RATIO COMPUTATION IN PRE- AND POST-SURGICAL VENTRICULOMEGALY.Proceedings. IEEE International Symposium on Biomedical Imaging · 2023
    Article
  8. Investigation of probability maps in deep-learning-based brain ventricle parcellation.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
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  15. Evaluating the impact of MR image harmonization on thalamus deep network segmentation.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Muhan ShaoDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Shuo HanDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Aaron CarassDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Xiang LiDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Ari M BlitzDepartment of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, MD 21287, USA.
Jerry L PrinceDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Lotta M EllingsenDepartment of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Johns Hopkins University · USNational Institutes of Health · US

Funding

Ventricle segmentation and labeling to characterize normal pressure hydrocephalusR21NS096497 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2016 to 2017
$426k
NINDS NIH HHS R21 NS096497
6 · The paper itself

Abstract

Normal Pressure Hydrocephalus (NPH) is a brain disorder that can present with ventriculomegaly and dementia-like symptoms, which often can be reversed through surgery. Having accurate segmentation of the ventricular system into its sub-compartments from magnetic resonance images (MRI) would be beneficial to better characterize the condition of NPH patients. Previous segmentation algorithms need long processing time and often fail to accurately segment severely enlarged ventricles in NPH patients. Recently, deep convolutional neural network (CNN) methods have been reported to have fast and accurate performance on medical image segmentation tasks. In this paper, we present a 3D U-net CNN-based network to segment the ventricular system in MRI. We trained three networks on different data sets and compared their performances. The networks trained on healthy controls (HC) failed in patients with NPH pathology, even in patients with normal appearing ventricles. The network trained on images from HC and NPH patients provided superior performance against state-of-the-art methods when evaluated on images from both data sets.

Indexed as

CNNHydrocephalusMRISegmentation

Identifiers

PMID33094293
PMCPMC7577585
OpenAlexW2897107060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.