ArticleInternational journal of bioprinting2017
Bioprinting of osteochondral tissues: A perspective on current gaps and future trends.
Article in International journal of bioprinting, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Integrating bioprinting, cell therapies and drug delivery towards in vivo regeneration of cartilage, bone and osteochondral tissue.Drug delivery and translational research · 2024Review
- Is 3D Printing Promising for Osteochondral Tissue Regeneration?ACS applied bio materials · 2023Review
- [Research advances on the construction of artificial dermal scaffolds based on biomaterials].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Review
- Portable hand-held bioprinters promote in situ tissue regeneration.Bioengineering & translational medicine · 2022Review
- miRNA induced 3D bioprinted-heterotypic osteochondral interface.Biofabrication · 2022Article
- Research progress on the biological modifications of implant materials in 3D printed intervertebral fusion cages.Journal of materials science. Materials in medicine · 2021Review
- Challenges and Innovations in Osteochondral Regeneration: Insights from Biology and Inputs from Bioengineering toward the Optimization of Tissue Engineering Strategies.Journal of functional biomaterials · 2021Review
- Hybrid Bioprinting of Zonally Stratified Human Articular Cartilage Using Scaffold-Free Tissue Strands as Building Blocks.Advanced healthcare materials · 2020Article
- Aspiration-assisted bioprinting of the osteochondral interface.Scientific reports · 2020Article
- Materials and technical innovations in 3D printing in biomedical applications.Journal of materials chemistry. B · 2020Review
- Bioengineering Approaches to Accelerate Clinical Translation of Stem Cell Therapies Treating Osteochondral Diseases.Stem cells international · 2020Review
- Locally Controlled Diffusive Release of Bone Morphogenetic Protein-2 Using Micropatterned Gelatin Methacrylate Hydrogel Carriers.Biochip journal · 2020Article
- Recent advances in biomaterials for 3D scaffolds: A review.Bioactive materials · 2019Article
- Bioactive scaffolds for osteochondral regeneration.Journal of orthopaedic translation · 2019Review
- Biofabrication for osteochondral tissue regeneration: bioink printability requirements.Journal of materials science. Materials in medicine · 2019Review
- Osteochondral tissue repair in osteoarthritic joints: clinical challenges and opportunities in tissue engineering.Bio-design and manufacturing · 2018Review
- IJB is on its way to Science Citation Index.International journal of bioprinting · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteochondral tissue regeneration has remained a critical challenge in orthopaedic surgery, especially due to complications of arthritic degeneration arising out of mechanical dislocations of joints. The common gold standard of autografting has several limitations in presenting tissue engineering strategies to solve the unmet clinical need. However, due to the complexity of joint anatomy, and tissue heterogeneity at the interface, the conventional tissue engineering strategies have certain limitations. The advent of bioprinting has now provided new opportunities for osteochondral tissue engineering. Bioprinting can uniquely mimic the heterogeneous cellular composition and anisotropic extra-cellular matrix (ECM) organization, while allowing for targeted gene delivery to achieve heterotypic differentiation. In this perspective, we discuss the current advances made towards bioprinting of composite osteochondral tissues and present an account of challenges-in terms of tissue integration, long-term survival, and mechanical strength at the time of implantation-required to be addressed for effective clinical translation of bioprinted tissues. Finally, we highlight some of the future trends related to osteochondral bioprinting with the hope of in-clinical translation.
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Registered trials
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