Evidence map›Paper›PMID 33094188›Full record

ArticleInternational journal of bioprinting2017

Printing amphotericin B on microneedles using matrix-assisted pulsed laser evaporation.

Roger Sachan, Panupong Jaipan, Jennifer Y Zhang, Simone Degan, Detlev Erdmann, Jonathan Tedesco, Lyndsi Vanderwal, Shane J Stafslien, Irina Negut, Anita Visan and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of bioprinting, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. IJB is on its way to Science Citation Index.International journal of bioprinting · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Roger SachanWake Early College of Health and Sciences, Raleigh, North Carolina, USA.
Panupong JaipanJoint Department of Biomedical Engineering, The University of North Carolina and North Carolina State University, Raleigh, North Carolina, USA.
Jennifer Y ZhangDepartment of Dermatology, Duke University Medical Center, Durham, North Carolina, USA.
Simone DeganDepartment of Dermatology, Duke University Medical Center, Durham, North Carolina, USA.
Detlev ErdmannDepartment of Surgery, Division of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Jonathan TedescoKeyence Corporation of America, Elmwood Park, New Jersey, USA.
Lyndsi VanderwalOffice of Research and Creativity Activity, North Dakota State University, 1715 Research Park Drive, Fargo ND, USA.
Shane J StafslienOffice of Research and Creativity Activity, North Dakota State University, 1715 Research Park Drive, Fargo ND, USA.
Irina NegutNational Institute for Lasers, Plasma and Radiation Physics, Lasers Department, P.O. Box MG-36, Bucharest-Magurele, Romania.
Anita VisanNational Institute for Lasers, Plasma and Radiation Physics, Lasers Department, P.O. Box MG-36, Bucharest-Magurele, Romania.
Gabriela DorciomanNational Institute for Lasers, Plasma and Radiation Physics, Lasers Department, P.O. Box MG-36, Bucharest-Magurele, Romania.
Gabriel SocolNational Institute for Lasers, Plasma and Radiation Physics, Lasers Department, P.O. Box MG-36, Bucharest-Magurele, Romania.
Rodica CristescuNational Institute for Lasers, Plasma and Radiation Physics, Lasers Department, P.O. Box MG-36, Bucharest-Magurele, Romania.
Douglas B ChriseyDepartment of Physics and Engineering Physics, Tulane University, New Orleans, LA, USA.
Roger J NarayanJoint Department of Biomedical Engineering, The University of North Carolina and North Carolina State University, Raleigh, North Carolina, USA.

Funding

JUN PROTEINS IN EPIDERMAL HOMEOSTASIS AND NEOPLASIAR01AR057746 · NIAMS · DUKE UNIVERSITY · PI ZHANG, JENNIFER YUNYAN · 2010 to 2014
$1.7M
NIAMS NIH HHS R01 AR057746
6 · The paper itself

Abstract

Transdermal delivery of amphotericin B, a pharmacological agent with activity against fungi and parasitic protozoa, is a challenge since amphotericin B exhibits poor solubility in aqueous solutions at physiologic pH values. In this study, we have used a laser-based printing approach known as matrix-assisted pulsed laser evaporation to print amphotericin B on the surfaces of polyglycolic acid microneedles that were prepared using a combination of injection molding and drawing lithography. In a modified agar disk diffusion assay, the amphotericin B-loaded microneedles showed concentration-dependent activity against the yeast

Indexed as

amphotericin Bantifungalmatrix-assisted pulsed laser evaporationmicroneedle

Identifiers

PMID33094188
PMCPMC7575625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.