ArticleInternational journal of particle therapy2020
The Importance of Verification CT-QA Scans in Patients Treated with IMPT for Head and Neck Cancers.
Article in International journal of particle therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Dosimetric evaluation of patient-side range shifters using two materials for superficial region treatment in spot scanning proton therapy: impact of material, air gap and setup distance.Journal of radiation research · 2026Article
- Optimizing QACT Frequency in Proton Therapy: Analysis of Standard Guidelines Across Treatment Sites.International journal of particle therapy · 2025Article
- Synthetic computed tomography techniques for adaptive proton therapy in head and neck cancers.Physics and imaging in radiation oncology · 2025Article
- Optimizing quality assurance CT schedules during adaptive proton therapy for enhanced patient care.Journal of applied clinical medical physics · 2025Article
- Clinical workload profile of medical physics professionals at particle therapy Centers: a National Survey in Japan.Journal of radiation research · 2025Article
- Cone-Beam CT Images as an Indicator of QACT During Adaptive Proton Therapy of Extremity Sarcomas.International journal of particle therapy · 2024Article
- Review
- Deformable CT image registration via a dual feasible neural network.Medical physics · 2022Article
- Analysis of the Rate of Re-planning in Spot-Scanning Proton Therapy.International journal of particle therapy · 2022Article
- Air variability in maxillary sinus during radiotherapy for sinonasal carcinoma.Clinical and translational radiation oncology · 2021Article
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Authors and funding
21 authors at 6 institutions in 1 country.
Funding
Abstract
purposeTo understand how verification computed tomography-quality assurance (CT-QA) scans influenced clinical decision-making to replan patients with head and neck cancer and identify predictors for replanning to guide intensity-modulated proton therapy (IMPT) clinical practice. PATIENTS AND
methodsWe performed a quality-improvement study by prospectively collecting data on 160 consecutive patients with head and neck cancer treated using spot-scanning IMPT who underwent weekly verification CT-QA scans. Kaplan-Meier estimates were used to determine the cumulative probability of a replan by week. Predictors for replanning were determined with univariate (UVA) and multivariate (MVA) Cox model hazard ratios (HRs). Logistic regression was used to determine odds ratios (ORs).
resultsOf the 160 patients, 79 (49.4%) had verification CT-QA scans, which prompted a replan. The cumulative probability of a replan by week 1 was 13.7% (95% confidence interval [CI], 8.82-18.9), week 2, 25.0% (95% CI, 18.0-31.4), week 3, 33.1% (95% CI, 25.4-40.0), week 4, 45.6% (95% CI, 37.3-52.8), and week 5 and 6, 49.4% (95% CI, 41.0-56.6). Predictors for replanning were sinonasal disease site (UVA: HR, 1.82,
conclusionsWeekly verification CT-QA scans frequently influenced clinical decision-making to replan. Additional studies that evaluate the practice of monitoring IMPT-treated patients with weekly CT-QA scans and whether that improves clinical outcomes are warranted.
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