Evidence map›Paper›PMID 33094093›Full record

ArticleLeukemia research reports2020

Myasthenia Gravis and Large Granular Lymphocytic Leukemia: a rare association.

Yumeng Zhang, Christa Varnadoe, Ankita Tandon, Peter Forsyth, Rami Komrokji, Lubomir Sokol

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yumeng ZhangMorsani College of Medicine, University of South Florida, Tampa Fl 33612.
Christa VarnadoeYale School of Nursing, New Haven CT 06510.
Ankita TandonMorsani College of Medicine, University of South Florida, Tampa Fl 33612.
Peter ForsythMoffitt Cancer Center, Tampa FL 33612.
Rami KomrokjiMoffitt Cancer Center, Tampa FL 33612.
Lubomir SokolMoffitt Cancer Center, Tampa FL 33612.
Moffitt Cancer Center · USUniversity of South Florida · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder sometimes observed in hematologic malignancies as a paraneoplastic syndrome. T-cell Large Granular Lymphocytic Leukemia (T-LGLL) is a rare lymphoproliferative clonal frequently associated with autoimmune disorders. Here we report two patients with T-LGLL who developed MG. In both patients the MG was bulbar without generalized weakness and did not involve the thymus. The treatment of T-LGLL led to the resolution of MG symptoms and decrease in acetylcholine receptor antibody titers in both patients suggesting a causative association.

Indexed as

Large Granular Lymphocytic LeukemiaMyasthenia gravis

Identifiers

PMID33094093
PMCPMC7568180
OpenAlexW3092554961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.