ArticleJournal of clinical imaging science2020
Percutaneous Bilateral Adrenal Radiofrequency Ablation in Severe Adrenocorticotropic Hormone-dependent Cushing Syndrome.
Article in Journal of clinical imaging science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Computed tomography-guided radiofrequency ablation of pheochromocytomas in a small case series with von Hippel-Lindau disease: treatment safety and outcomes.Abdominal radiology (New York) · 2026Article
- Efficiency of Microwave Ablation for Cortisol-Producing Adrenal Adenomas: Case Series and a Literature Review.Acta medica Lituanica · 2025Article
- Proceedings from an international consensus meeting on ablation in urogenital diseases.Insights into imaging · 2024Article
- Utilization of bilateral percutaneous microwave ablation of the adrenal glands in ectopic Cushing's syndrome.Radiology case reports · 2022Article
- Novel Protocol for CT-Guided Percutaneous Ablation of Hyperplastic Adrenal Glands in Cushing Syndrome.Cardiovascular and interventional radiology · 2022Article
- Image-Guided Percutaneous Ablation for Primary and Metastatic Tumors.Diagnostics (Basel, Switzerland) · 2022Review
- Thermal ablation in adrenal disorders: a discussion of the technology, the clinical evidence and the future.Current opinion in endocrinology, diabetes, and obesity · 2021Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objectives of the study were to evaluate adrenal radiofrequency ablation (RFA) as a method of treatment in patients with severe adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome, among whom bilateral adrenalectomy is not a suitable option. MATERIAL AND
methodsFive patients with ACTH-dependent Cushing syndrome underwent RFA of both adrenal glands. Four of them presented with Cushing disease unsuccessfully treated with pituitary surgery and medical therapy, while one patient had ACTH-dependent Cushing syndrome due to pancreatic endocrine tumor with liver metastases. All patients were disqualified from adrenalectomy due to morbid obesity or lack of consent.
resultsA technical success was obtained in all cases, with only one re-intervention necessitated by a cooling effect of the inferior vena cava. Despite pre-procedural adrenergic blockade, severe hypertension was noted during the procedure in three cases, this being treated immediately using direct-acting vasodilators. No complications occurred otherwise. In all cases, significant improvement of clinical symptoms was observed, as well as marked decreases in levels of serum cortisol, free urine cortisol, and dehydroepiandrosterone sulfate.
conclusionBilateral RFA under CT-guidance is technically feasible and clinical improvement can be achieved using the method. In patients disqualified from adrenal surgery, RFA might be considered as an alternative method of ACTH-dependent Cushing syndrome treatment.
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Registered trials
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