Evidence map›Paper›PMID 33093947›Full record

ArticleF1000Research2020

ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial.

Andrew Davies, Sharon Barrans, Cathy Burton, Katy Mercer, Joshua Caddy, Fay Chinnery, Laura Day, Diana Fernando, Kirit Ardeshna, Graham Collins and 5 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. InactivatingEJHaem · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Andrew DaviesSouthampton Experimental Cancer Medicine Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southhampton, UK.ORCID 0000-0002-7517-6938
Sharon BarransLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Cathy BurtonLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Katy MercerSouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Joshua CaddySouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Fay ChinnerySouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.ORCID 0000-0002-8082-9016
Laura DaySouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Diana FernandoSouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Kirit ArdeshnaUniversity College London Hospitals NHS Foundation Trust, London, UK.
Graham CollinsOxford University Hospitals NHS Trust, Oxford, UK.
John RadfordUniversity of Manchester, Manchester, UK.
Simon RulePlymouth Hospitals NHS Trust and Plymouth University Peninsula School of Medicine and Dentistry, Plymouth, UK.
Andrew McMillanNottingham University Hospitals NHS Trust, Nottingham, UK.
Peter JohnsonSouthampton Experimental Cancer Medicine Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southhampton, UK.
Gareth GriffithsSouthampton Clinical Trials Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
University Hospital Southampton NHS Foundation Trust · GBLeeds Teaching Hospitals NHS Trust · GBNottingham University Hospitals NHS Trust · GBOxford University Hospitals NHS Trust · GBPlymouth Hospital · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

Cancer Research UK 25352
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphoma, Large B-Cell, DiffusePrednisoloneAdultAntineoplastic Combined Chemotherapy ProtocolsBenzamidesClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicCyclophosphamideDoxorubicinHumansMulticenter Studies as TopicPyrazinesRituximabVincristineacalabrutinibBenzamidesCyclophosphamideDoxorubicinPrednisolonePyrazinesRituximabVincristineacalabrutinibBtk inhibitorDiffuse large B-cell lymphomamolecular profilingphase I/IIR-CHOP

Identifiers

PMID33093947
PMCPMC7551525
OpenAlexW3047660169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.