Trial reportJournal of interventional cardiology2020
Transcatheter Closure of Patent Ductus Arteriosus under Echocardiography Guidance: A Randomized Controlled Noninferiority Trial.
Trial report in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety and Efficacy of Zero Fluoroscopy Patent Ductus Arteriosus Closure in Comparison to the Standardized Fluoroscopy-Guided Procedure: A Systematic Review and Meta-Analysis.Current cardiology reviews · 2025Pooled it
- Expert consensus on bedside transcatheter closure of patent ductus arteriosus in extremely low birth weight infants.Pediatric research · 2026Article
- Transcatheter closure of PDA: how the pathway changed from classical fluoroscopy approach.Frontiers in cardiovascular medicine · 2026Article
- Complications of Interventional Versus Surgical Closure of Patent Ductus Arteriosus in Very Preterm Infants-A Retrospective Analysis.Journal of cardiovascular development and disease · 2025Article
- Design and Rationale of ECHO-CLIP Study: Transcatheter Edge-to-Edge Repair for Mitral Regurgitation Under Solely Transesophageal Echocardiographic Guidance Compared With Fluoroscopic and Transesophageal Echocardiographic Coguidance.Journal of the American Heart Association · 2025Article
- Application of single venous approach under echocardiography without angiography in closure of Patent Ductus Arteriosus.Journal of cardiothoracic surgery · 2024Article
- Transesophageal echocardiography-guided percutaneous patent ductus arteriosus closure without fluoroscopy.Journal of cardiothoracic surgery · 2023Article
- Transcatheter Device Therapy and the Integration of Advanced Imaging in Congenital Heart Disease.Children (Basel, Switzerland) · 2022Review
- Evaluation of Cardiac Function Characteristics after Patent Ductus Arteriosus Closure in Children and Adults by Echocardiographic Data.Computational and mathematical methods in medicine · 2022Article
- Transcatheter Closure of Patent Ductus Arteriosus via Different Approaches.Frontiers in cardiovascular medicine · 2021Article
- Use of echocardiography in percutaneous closure of patent ductus arteriosus at the Instituto Nacional de Salud del Niño, San Borja, Lima - Peru.Archivos peruanos de cardiologia y cirugia cardiovascularArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous occlusion under fluoroscopy guidance has become the preferred method for the treatment of patent ductus arteriosus (PDA). To avoid radiation exposure and contrast agent use, PDA occlusion under transthoracic echocardiography (TTE) guidance was conducted.
objectivesWe assessed the hypothesis that the success rate of percutaneous PDA occlusion under TTE was noninferior to that under fluoroscopy guidance.
methodsIn this single-center trial, 100 patients were randomly assigned in a 1 : 1 ratio to the TTE group (
resultsPatient, defect, and device characteristics were similarly distributed between groups. The success rate of occlusion was 98% for the TTE group and 100% for the fluoroscopy group (absolute difference: -2%; 95% confidence interval: -5.9% to 1.9%). Cost and procedure duration were significantly lower in the TTE group, without adverse events in either group at a median of 12.0 months (range, 10.0-15.5 months) of follow-up.
conclusionPercutaneous PDA occlusion can be performed via TTE guidance safely and effectively, and the success rate of the TTE-guided procedure was noninferior to that under fluoroscopy guidance, with reduced cost and procedure time. The trial is registered with http://www.chictr.org.cn (ChiCTR-ICR-15006334).
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