ReviewCurrent genomics2020
The Association of Sleep Disorders, Obesity and Sleep-Related Hypoxia with Cancer.
Registry-linked trialOpen access · greenAbstract readReview
In one paragraph
Review in Current genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05093426 (Personalised Electronic Record Supported Two-Stage Observational Study of Sleep in Patients With Breast Cancer), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalised Electronic Record Supported Two-Stage Observational Study of Sleep in Patients With Breast Cancer
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Pooled it
- Characteristics and influencing factors of sleep disturbance in breast cancer patients: a cross-sectional study.Frontiers in oncology · 2026Article
- Causal Association Between Sleep Traits and Endometriosis: A Mendelian Randomization Study.International journal of women's health · 2026Article
- Relationship between daytime napping duration and pan-cancer risk: a prospective cohort study based on the China Health and Retirement Longitudinal Study (CHARLS).Journal of health, population, and nutrition · 2025Article
- Integrative sleep management: from molecular pathways to conventional and herbal treatments.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Life's essential 8 and specific cancer risk and mortality in men and women: a population-based cohort analysis of 332,417 United Kingdom participants.BMC cancer · 2025Article
- Metabolic underpinnings of cancer-related fatigue.American journal of physiology. Endocrinology and metabolism · 2024Review
- Elucidating sleep disorders: a comprehensive bioinformatics analysis of functional gene sets and hub genes.Frontiers in immunology · 2024Article
- Sleep Behaviors, Genetic Predispositions, and Risk of Esophageal Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Circadian-mediated regulation of cardiometabolic disorders and aging with time-restricted feeding.Obesity (Silver Spring, Md.) · 2023Review
- Incidence disparities of obstructive sleep apnea-associated lung cancer by gender; Korean National Health Insurance data analysis.Frontiers in oncology · 2023Article
- Global research on cancer and sleep: A bibliometric and visual analysis of the last two decades.Frontiers in neurology · 2023Review
- Association of a Healthy Lifestyle with All-Cause, Cause-Specific Mortality and Incident Cancer among Individuals with Metabolic Syndrome: A Prospective Cohort Study in UK Biobank.International journal of environmental research and public health · 2022Article
- Neuropsychiatric Disorders and Frailty in Older Adults over the Spectrum of Cancer: A Narrative Review.Cancers · 2022Review
- Cross-Cultural Adaptation, Reliability, and Psychophysical Validation of the Pain and Sleep Questionnaire Three-Item Index in Finnish.Journal of clinical medicine · 2021Article
- Intergenic SNPs in Obstructive Sleep Apnea Syndrome: Revealing Metabolic, Oxidative Stress and Immune-Related Pathways.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 8 institutions in 4 countries.
Anna Brzecka1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Karolina Sarul1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Tomasz Dyła1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Marco Avila-Rodriguez1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Ricardo Cabezas-Perez1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Vladimir N Chubarev1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Nina N Minyaeva1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Sergey G Klochkov1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Margarita E Neganova1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Liudmila M Mikhaleva1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Siva G Somasundaram1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Cecil E Kirkland1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Vadim V Tarasov1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Gjumrakch Aliev1Department of Pulmonary Diseases and Lung Cancer, Wroclaw Medical University, Wrocław, Poland; 2Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia; 3Departamento de Nutrición y Bioquímica, Grupo de Investigación Bioquímica Experimental y Computacional, Pontificia Universidad Javeriana, Bogotá, Colombia; 4I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russia; 5National Research University Higher School of Economics, 20 Myasnitskaya Street, Moscow, 101000, Russia; 6Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russia; 7Research Institute of Human Morphology, 3 Tsyurupy Street, Moscow, 117418, Russia; 8Department of Biological Sciences, Salem University, Salem, WV, 26426, USA; 9GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.
Sechenov University · RUWroclaw Medical University · PLInstitute of Physiologically Active Compounds · RUSalem University · USNational Research University Higher School of Economics · RUPontificia Universidad Javeriana · COResearch Institute of Human Morphology · RUUniversity of Tolima · CO
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleep disorders have emerged as potential cancer risk factors.
objectiveThis review discusses the relationships between sleep, obesity, and breathing disorders with concomitant risks of developing cancer.
resultsSleep disorders result in abnormal expression of clock genes, decreased immunity, and melatonin release disruption. Therefore, these disorders may contribute to cancer development. Moreover, in sleep breathing disorder, which is frequently experienced by obese persons, the sufferer experiences intermittent hypoxia that may stimulate cancer cell proliferation. DISCUSSION: During short- or long- duration sleep, sleep-wake rhythm disruption may occur. Insomnia and obstructive sleep apnea increase cancer risks. In short sleepers, an increased risk of stomach cancer, esophageal squamous cell cancer, and breast cancer was observed. Among long sleepers (>9 hours), the risk of some hematologic malignancies is elevated.
conclusionSeveral factors including insomnia, circadian disruption, obesity, and intermittent hypoxia in obstructive sleep apnea are contributing risk factors for increased risk of several types of cancers. However, further studies are needed to determine the more significant of these risk factors and their interactions.
Indexed as
Cancerintermittent hypoxiaobesityrisk factorssleepsleep apnea
Identifiers
What OpenQuestion holds
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LicenceCC BY-NC
Read underepoch 390
Registered trials
NCT05093426ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.