Evidence map›Paper›PMID 33093776›Full record

ArticleSarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG2020

Sarcoidosis and increased risk of comorbidities and mortality in sweden.

Johanna Larsson, Pål Graff, Ing-Liss Bryngelsson, Per Vihlborg

Open access · greenAbstract read
In one paragraph

Article in Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Autoantibodies in sarcoidosis: Innocent bystander or promising biomarker for organ involvement?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  5. Article
  6. Article
  7. Infectious Complications of Pulmonary Sarcoidosis.Journal of clinical medicine · 2024
    Review
  8. Article
  9. Renal replacement therapy in sarcoidosis.Frontiers in medicine · 2022
    Review
  10. Tackling Health Care Disparities: How to Build a Sarcoidosis Center.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2022
    Review
  11. Article
  12. Article
  13. Sarcoidosis: a prospective observational cohort from Northern Alberta.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Johanna LarssonDepartment of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden.
Pål GraffNational Institute of Occupational Health, Department of Chemical and Biological Work Environment, Oslo, Norway.
Ing-Liss BryngelssonDepartment of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden.
Per VihlborgDepartment of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden.
Örebro University Hospital · SENational Institute of Occupational Health · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSarcoidosis is a systemic inflammatory disorder, with an unclear etiology, involving granuloma formation that in most cases affects the lungs and intrathoracic lymph nodes. Sarcoidosis occurs in an acute or chronic form, each with different clinical presentation and prognosis.

methodsCase-control study of comorbidity and mortality in people diagnosed with sarcoidosis (ICD10 code D86) from 2007 through 2016 in Sweden. Controls were matched to cases (2:1) based on age, sex and county at the time of diagnosis. Data was collected from the Swedish National Patient Register and The Cause of Death Register. All men and women aged 20-65 years old who were diagnosed with sarcoidosis (D86, ICD10) during the years of study were included, resulting 7828 cases and 15656 controls.

resultsPatients with sarcoidosis had increased mortality compared to matched controls (hazard ratio 1.88; 95% CI 1.56 - 2.26) and the Swedish general population (standardized mortality ratios1.75; 95% CI 1.52 - 2.00). The sarcoid cases, compared to controls, also had a significantly greater number of inpatient visits within several different chapters of ICD10 e.g. cardiomyopathy, heart failure, pulmonary embolism and malignant neoplasm.

conclusionIndividuals with sarcoidosis are at higher risk of comorbidities and mortality than matched controls as well as the general population of Sweden. These findings are important knowledge for healthcare professionals who meet sarcoid patients, to encourage identification and treatment of comorbidities to reduce the risk of impaired quality of life and, eventually, premature death.

Indexed as

AdultAgedCase-Control StudiesCause of DeathComorbidityDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle AgedPrognosisRegistriesRisk FactorsSarcoidosisSwedenCase controlComorbidityMortalitySarcoidosis

Identifiers

PMID33093776
PMCPMC7569548
OpenAlexW3093714358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.