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ArticleSarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG2020

Interstitial lung disease and microscopic polyangiitis in chilean patients.

Pamela Wurmann, Francisca Sabugo, Fabian Elgueta, Macarena Mac-Namara, Karen Vergara, Daniela Vargas, Maria Luisa Molina, Juan Carlos Díaz, Hector Gatica, Annelise Goecke

Open access · greenAbstract read
In one paragraph

Article in Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Original Article: Clinical Research.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Pamela WurmannRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Francisca SabugoRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Fabian ElguetaRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Macarena Mac-NamaraRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Karen VergaraRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Daniela VargasRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Maria Luisa MolinaRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Juan Carlos DíazRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Hector GaticaRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Annelise GoeckeRheumatology section, Department of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.
Hospital Clínico de la Universidad de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the clinical and serological patients characteristics with Microscopic Polyangiitis (MPA) and Interstitial lung disease (ILD).

methodsOf all the patients with AAV diagnosed between 2007-2017 at the Hospital Clinico Universidad de Chile, those with MPA and ILD were selected and studied retrospectively.

resultsAll patients were Hispanic; median age at diagnosis 65 years (32-84). 59% were female. All were positive for p-ANCA, 16 patients for MPO. Most common manifestations were constitutional symptoms, weight loss and fever. CT-Scans patterns were Usual Interstitial Pneumonia (UIP) in 10 patients, Nonspecific Interstitial Pneumonia (NSIP) in 6 and fibrosis not UIP or NSIP pattern in 1. In 6 cases, ILD was diagnosed 0.5-14 years before MPA and concomitantly in 11.

conclusionsAlthough infrequent, Microscopic Polyangiitis should be suspected in patients with ILD particularly if extra-pulmonary manifestations that rise the possibility of a systemic illness are present, regardless of the time elapsed between the latter and the diagnosis of this type of lung involvement.

Indexed as

AdultAgedAged, 80 and overAntibodies, Antineutrophil CytoplasmicBiomarkersChileFemaleHumansLung Diseases, InterstitialMaleMicroscopic PolyangiitisMiddle AgedPeroxidasePredictive Value of TestsPrognosisRetrospective StudiesAntibodies, Antineutrophil CytoplasmicBiomarkersMPO protein, humanPeroxidaseANCA vasculitisinterstitial lung diseasemicroscopic polyangiitis

Identifiers

PMID33093767
PMCPMC7569542
OpenAlexW3017322484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.