Evidence map›Paper›PMID 33093643›Full record

ArticleCancer gene therapy2021

B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation.

Cinzia Giagulli, Francesca Caccuri, Simone Zorzan, Antonella Bugatti, Alberto Zani, Federica Filippini, Ekta Manocha, Pasqualina D'Ursi, Alessandro Orro, Riccardo Dolcetti and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Cancer gene therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  11. HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Article
  13. Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Cinzia GiagulliSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.
Francesca CaccuriSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.
Simone ZorzanPlantech, Environmental Research and Innovation (ERIN) Department, Luxembourg Institute of Science & Technology (LIST), L-4422, Belvaux, Luxembourg.
Antonella BugattiSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.ORCID http://orcid.org/0000-0001-5450-5774
Alberto ZaniSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.ORCID http://orcid.org/0000-0001-9066-7973
Federica FilippiniSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.ORCID http://orcid.org/0000-0003-1598-8317
Ekta ManochaSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy.
Pasqualina D'UrsiDepartment of Biomedical Sciences, Institute for Biomedical Technologies e National Research Council (ITB-CNR), 20090, Segrate (MI), Italy.ORCID http://orcid.org/0000-0003-1554-429X
Alessandro OrroDepartment of Biomedical Sciences, Institute for Biomedical Technologies e National Research Council (ITB-CNR), 20090, Segrate (MI), Italy.ORCID http://orcid.org/0000-0002-2581-9579
Riccardo DolcettiUniversity of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0003-1625-9853
Arnaldo CarusoSection of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, 25123, Brescia, Italy. arnaldo.caruso@unibs.it.ORCID http://orcid.org/0000-0001-5178-566X
University of Brescia · ITNational Academies of Sciences, Engineering, and Medicine · USLuxembourg Institute of Science and Technology · LUTranslational Research Institute · AU

Funding

Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) 14287Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) 20108
6 · The paper itself

Abstract

Combined antiretroviral therapy (cART) for HIV-1 dramatically slows disease progression among HIV

Indexed as

CarcinogenesisEpidermal Growth Factorgag Gene Products, Human Immunodeficiency VirusHIV-1HIV AntigensHIV InfectionsHumansLymphocyte ActivationLymphomaOncogene Protein v-aktPhosphatidylinositol 3-KinasesReceptor, PAR-1Signal TransductionTranscriptional ActivationEpidermal Growth Factorgag Gene Products, Human Immunodeficiency VirusHIV AntigensOncogene Protein v-aktp17 protein, Human Immunodeficiency Virus Type 1Phosphatidylinositol 3-KinasesReceptor, PAR-1

Identifiers

PMID33093643
PMCPMC8203498
OpenAlexW3093524854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.