ArticleThe ISME journal2021
The evolution of coexistence from competition in experimental co-cultures of Escherichia coli and Saccharomyces cerevisiae.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 48 citations in OpenAlex.
- Analysis and engineering of quorum sensing-based communications between bacteria and fungi.mBio · 2026Review
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- Stable coexistence and phenol-degradation expression of Cupriavidus sp. strain P-10 and Comamonas thiooxydans strain R2 in phenol-competitive chemostat culture.Applied microbiology and biotechnology · 2025Article
- Evolution of One Species Increases Resistance to Invasion in a Simple Synthetic Community.Microbial ecology · 2025Article
- Impact of Virus-Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Co-Existence Slows Diversification in Experimental Populations of E. coli and P. fluorescens.Environmental microbiology · 2025Article
- Phocaeicola vulgatus shapes the long-term growth dynamics and evolutionary adaptations of Clostridioides difficile.Cell host & microbe · 2025Article
- Empirical evidence of resource dependent evolution of payoff matrices in Saccharomyces cerevisiae populations.Journal of evolutionary biology · 2025Article
- Algorithm of spatial-temporal simulation for environment-strain interactions in strain-strain consortia based on resource competition mechanism.Computational and structural biotechnology journal · 2024Article
- Predicting the first steps of evolution in randomly assembled communities.Nature communications · 2024Article
- The evolution of autonomy from two cooperative specialists in fluctuating environments.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community.Nature communications · 2024Article
- Human gut microbiota interactions shape the long-term growth dynamics and evolutionary adaptations ofbioRxiv : the preprint server for biology · 2024Article
- Predicting the First Steps of Evolution in Randomly Assembled Communities.bioRxiv : the preprint server for biology · 2024Article
- Emergence and maintenance of stable coexistence during a long-term multicellular evolution experiment.Nature ecology & evolution · 2024Article
- Carbon starvation raises capacities in bacterial antibiotic resistance and viral auxiliary carbon metabolism in soils.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Metabolic insights from mass spectrometry imaging of biofilms: A perspective from model microorganisms.Methods (San Diego, Calif.) · 2024Review
- Eco-evolutionary feedbacks in the human gut microbiome.Nature communications · 2023Article
- A fitness trade-off between growth and survival governed by Spo0A-mediated proteome allocation constraints inScience advances · 2023Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial communities are comprised of many species that coexist on small spatial scales. This is difficult to explain because many interspecies interactions are competitive, and ecological theory predicts that one species will drive the extinction of another species that competes for the same resource. Conversely, evolutionary theory proposes that natural selection can lead to coexistence by driving competing species to use non-overlapping resources. However, evolutionary escape from extinction may be slow compared to the rate of competitive exclusion. Here, we use experimental co-cultures of Escherichia coli and Saccharomyces cerevisiae to study the evolution of coexistence in species that compete for resources. We find that while E. coli usually outcompetes S. cerevisiae in co-culture, a few populations evolved stable coexistence after ~1000 generations of coevolution. We sequenced S. cerevisiae and E. coli populations, identified multi-hit genes, and engineered alleles from these genes into several genetic backgrounds, finding that some mutations modified interactions between E. coli and S. cerevisiae. Together, our data demonstrate that coexistence can evolve, de novo, from intense competition between two species with no history of coevolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.