Evidence map›Paper›PMID 33093526›Full record

ArticleScientific reports2020

Synthesis, characterization of two matrine derivatives and their cytotoxic effect on Sf9 cell of Spodoptera frugiperda.

Huiqing He, Xiangjing Qin, Fangyun Dong, Jingmin Ye, Chunbao Xu, Hanhui Zhang, Zhanmei Liu, Xiaojing Lv, Yuehua Wu, Xuhong Jiang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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  12. Advances in Control Strategies againstMolecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Huiqing HeInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Xiangjing QinCAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences (CAS), Guangzhou, 510301, China.
Fangyun DongInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Jingmin YeInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Chunbao XuDepartment of Chemical and Biochemical Engineering, Western University, London, Ontario, N6A5B9, Canada.
Hanhui ZhangInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Zhanmei LiuInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Xiaojing LvInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Yuehua WuInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Xuhong JiangInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China. jiangxh69@163.com.
Xingan ChengInstitute of Natural Product Chemistry, College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China. anzai_28@163.com.
Zhongkai University of Agriculture and Engineering · CNInstitute of Oceanology · CNWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The invasion of Spodoptera frugiperda has imposed a serious impact on global food security. Matrine is a botanical pesticide with a broad spectrum of insecticidal activity which was recommended for controlling Spodoptera frugiperda. In order to discover effective insecticide for Spodoptera frugiperda, two matrine derivatives modified with carbon disulfide and nitrogen-containing groups were systhesized. And their inhibition activities on Sf9 cell were evaluated. The structural configuration of compounds were characterized by IR, HPLC, MS, NMR and XRD, with yields of 52% and 65%, respectively. The IC

Indexed as

AlkaloidsAnimalsApoptosisCell ProliferationInsecticidesMatrinesQuinolizinesSf9 CellsSpodopteraAlkaloidsInsecticidesMatrinesQuinolizines

Identifiers

PMID33093526
PMCPMC7581774
OpenAlexW3094398256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.