ArticleNature communications2020
Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Enhanced electrochemically-directed oligonucleotide synthesis via porous silica thin-film for DNA data storage.Microsystems & nanoengineering · 2026Article
- Programmable one-pot polymerase-mediated DNA synthesis via temperature control.Nature communications · 2026Article
- DNA Data Storage Architecture via Ligation of Dynamic DNA Bytes.Small methods · 2026Article
- Benchmarking DNA barcode decoding strategies under high error rates.BMC bioinformatics · 2026Article
- ZAT-DNA enables DNA data storage with molecular-layer non-replicability.Nature communications · 2026Article
- Large-Scale Distribution of Physical Data Using DNA-of-Things Technology in Newspaper Printing.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- From spacecraft ranging to massive DNA data storage: Composite ranging codes as indices and error correction references.Science advances · 2026Article
- Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage.Nature communications · 2026Article
- Error characterization and error correction approaches in combinatorial DNA-based storage.Scientific reports · 2026Article
- Linked data storage using DNA origami nanostructures.Nature communications · 2025Article
- DVOUG enables robust DNA sequence assembly and reconstruction with a dynamic, variable-order graph.Cell reports methods · 2025Article
- Fabrication of microcolumn arrays for high-throughput oligonucleotide synthesis using 3D printing.Scientific reports · 2025Article
- Efficient trace reconstruction in DNA storage systems using bidirectional beam search.iScience · 2025Article
- Efficiency of Digital Photolithographic Synthesis of Large, High-Quality DNA Libraries and Microarrays using a Guanine OCommunications chemistry · 2025Article
- DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage.Nature communications · 2025Article
- A compact cassette tape for DNA-based data storage.Science advances · 2025Article
- Dna-storalator: a computational simulator for DNA data storage.BMC bioinformatics · 2025Article
- Primer-Disk-Enabled DNA Data Storage System with Index and Record-Many-Read-Many Features.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025Review
- Cost-Effective DNA Storage System with DNA Movable Type.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. The current hamstring of DNA data storage systems-both in cost and speed-is synthesis. The key idea for breaking this bottleneck pursued in this work is to move beyond the low-error and expensive synthesis employed almost exclusively in today's systems, towards cheaper, potentially faster, but high-error synthesis technologies. Here, we demonstrate a DNA storage system that relies on massively parallel light-directed synthesis, which is considerably cheaper than conventional solid-phase synthesis. However, this technology has a high sequence error rate when optimized for speed. We demonstrate that even in this high-error regime, reliable storage of information is possible, by developing a pipeline of algorithms for encoding and reconstruction of the information. In our experiments, we store a file containing sheet music of Mozart, and show perfect data recovery from low synthesis fidelity DNA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.