Evidence map›Paper›PMID 33093275›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2020

Open channel block of Kv1.4 potassium channels by aripiprazole.

Jeaneun Park, Kwang-Hyun Cho, Hong Joon Lee, Jin-Sung Choi, Duck-Joo Rhie

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Shaping the Action Potential in Dorsal Root and Trigeminal Ganglia Neurons: Relevance to Pain Mechanisms.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  3. Article
  4. Effects of rosiglitazone, an antidiabetic drug, on Kv3.1 channels.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
  5. Article
  6. The antidiabetic drug rosiglitazone blocks Kv1.5 potassium channels in an open state.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeaneun ParkDepartment of Physiology, 3Catholic Neuroscience Institute, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Kwang-Hyun ChoDepartment of Physiology, 3Catholic Neuroscience Institute, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Hong Joon LeeDepartment of Physiology, 3Catholic Neuroscience Institute, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jin-Sung ChoiCollege of Pharmacy, Integrated Research Institute of Pharmaceutical, The Catholic University of Korea, Bucheon 14662, Korea.
Duck-Joo RhieDepartment of Physiology, 3Catholic Neuroscience Institute, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aripiprazole is a quinolinone derivative approved as an atypical antipsychotic drug for the treatment of schizophrenia and bipolar disorder. It acts as with partial agonist activities at the dopamine D2 receptors. Although it is known to be relatively safe for patients with cardiac ailments, less is known about the effect of aripiprazole on voltage-gated ion channels such as transient A-type K

Indexed as

Atypical antipsychoticsInactivation kineticsKv1.4 channelOpen channel blockUse dependent

Identifiers

PMID33093275
PMCPMC7585592
OpenAlexW3094596703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.