Evidence map›Paper›PMID 33093210›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The polar Ras-like GTPase MglA activates type IV pilus via SgmX to enable twitching motility in

Romain Mercier, Sarah Bautista, Maëlle Delannoy, Margaux Gibert, Annick Guiseppi, Julien Herrou, Emilia M F Mauriello, Tâm Mignot

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Milestones in the development ofJournal of bacteriology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Tight-packing of large pilin subunits provides distinct structural and mechanical properties for theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Methods and Measures for Investigating Microscale Motility.Integrative and comparative biology · 2023
    Review
  13. Article
  14. Article
  15. Bacterial Motility and Its Role in Skin and Wound Infections.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. eLife · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Romain MercierAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France rmercier@imm.cnrs.fr tmignot@imm.cnrs.fr.
Sarah BautistaAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.
Maëlle DelannoyAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.ORCID 0000-0003-2504-5611
Margaux GibertAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.
Annick GuiseppiAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.
Julien HerrouAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.ORCID 0000-0002-8585-8043
Emilia M F MaurielloAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France.ORCID 0000-0001-9770-6138
Tâm MignotAix-Marseille Université-CNRS (UMR7283), Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, 13009 Marseille, France rmercier@imm.cnrs.fr tmignot@imm.cnrs.fr.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type IV pili (Tfp) are highly conserved macromolecular structures that fulfill diverse cellular functions, such as adhesion to host cells, the import of extracellular DNA, kin recognition, and cell motility (twitching). Outstandingly, twitching motility enables a poorly understood process by which highly coordinated groups of hundreds of cells move in cooperative manner, providing a basis for multicellular behaviors, such as biofilm formation. In the social bacteria

Indexed as

Bacterial ProteinsCell PolarityFimbriae, BacterialMonomeric GTP-Binding ProteinsMyxococcus xanthusPolymorphism, Single NucleotideWhole Genome SequencingBacterial ProteinsMglA protein, Myxococcus xanthusMonomeric GTP-Binding Proteinscell motilityMyxococcus xanthussmall GTPasetype IV pilus

Identifiers

PMID33093210
PMCPMC7668184
OpenAlexW3093751859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.