Evidence map›Paper›PMID 33092310›Full record

ArticlePolymers2020

Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers.

Shixiong Kang, Shicong Hou, Xunwei Chen, Deng-Guang Yu, Lin Wang, Xiaoyan Li, Gareth R Williams

Erratum issuedAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Electrospun nanofibers and their application as sensors for healthcare.Frontiers in bioengineering and biotechnology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shixiong KangSchool of Materials Science & Engineering, University of Shanghai for Science & Technology, 516 Jungong Road, Shanghai 200093, China.ORCID 0000-0002-0764-6731
Shicong HouSchool of Materials Science & Engineering, University of Shanghai for Science & Technology, 516 Jungong Road, Shanghai 200093, China.
Xunwei ChenSchool of Materials Science & Engineering, University of Shanghai for Science & Technology, 516 Jungong Road, Shanghai 200093, China.
Deng-Guang YuSchool of Materials Science & Engineering, University of Shanghai for Science & Technology, 516 Jungong Road, Shanghai 200093, China.ORCID 0000-0001-7825-4498
Lin WangShanghai Institute of Technical Physics, Chinese Academy of Sciences, 500 Yutian Road, Shanghai 200083, China.
Xiaoyan LiSchool of Materials Science & Engineering, University of Shanghai for Science & Technology, 516 Jungong Road, Shanghai 200093, China.
Gareth R WilliamsUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0002-3066-2860

Funding

The Natural Science Foundation of Shanghai 20ZR1439000
6 · The paper itself

Abstract

Although electrospun nanofibers are expanding their potential commercial applications in various fields, the issue of energy savings, which are important for cost reduction and technological feasibility, has received little attention to date. In this study, a concentric spinneret with a solid Teflon-core rod was developed to implement an energy-saving electrospinning process. Ketoprofen and polyvinylpyrrolidone (PVP) were used as a model of a poorly water-soluble drug and a filament-forming matrix, respectively, to obtain nanofibrous films via traditional tube-based electrospinning and the proposed solid rod-based electrospinning method. The functional performances of the films were compared through in vitro drug dissolution experiments and ex vivo sublingual drug permeation tests. Results demonstrated that both types of nanofibrous films do not significantly differ in terms of medical applications. However, the new process required only 53.9% of the energy consumed by the traditional method. This achievement was realized by the introduction of several engineering improvements based on applied surface modifications, such as a less energy dispersive air-epoxy resin surface of the spinneret, a free liquid guiding without backward capillary force of the Teflon-core rod, and a smaller fluid-Teflon adhesive force. Other non-conductive materials could be explored to develop new spinnerets offering good engineering control and energy savings to obtain low-cost electrospun polymeric nanofibers.

Indexed as

electrospinningenergy savingengineering optimizationfast dissolutionpoorly water-soluble drug

Identifiers

PMID33092310
PMCPMC7589577

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.