Evidence map›Paper›PMID 33092268›Full record

ArticleInternational journal of molecular sciences2020

Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.

Junghwa Choi, Jee Young Sung, Saerom Lee, Jungyoen Yoo, Christopher Rongo, Yong-Nyun Kim, Jaegal Shim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway.Journal of experimental & clinical cancer research : CR · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Rab GTPases: Central Coordinators of Membrane Trafficking in Cancer.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Junghwa ChoiResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
Jee Young SungResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
Saerom LeeResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
Jungyoen YooResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
Christopher RongoWaksman Institute of Microbiology, Rutgers, The State University of New Jersey, 190 Frelinghuysen Road, Piscataway, NJ 08854, USA.ORCID 0000-0002-1361-5288
Yong-Nyun KimResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
Jaegal ShimResearch Institute of National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-do 10408, Korea.
National Cancer Center · KRRutgers, The State University of New Jersey · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Synapse Formation in the C. elegans Nervous SystemR01NS042023 · NINDS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RONGO, CHRISTOPHER G · 2002 to 2018
$4.6M
Genetics Analysis of Neuronal Hypoxic Stress ResistanceR01GM101972 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI RONGO, CHRISTOPHER G · 2012 to 2024
$4.1M
National Cancer Center Korea NCC-1810293National Cancer Center Korea NCC-1810932National Research Foundation of Korea NRF-2015R1D1A1A01060359NIGMS NIH HHS R01 GM101972NIH HHS P40 OD010440NINDS NIH HHS R01 NS042023
6 · The paper itself

Abstract

The epidermal growth factor receptor (EGFR) signaling is important for normal development, such as vulval development in

Indexed as

AnimalsCaenorhabditis elegansCarcinoma, Non-Small-Cell LungCell Line, TumorDisease Models, AnimalErbB ReceptorsErlotinib HydrochlorideGefitinibGerminal Center KinasesHumansLung NeoplasmsMutationProtein Kinase Inhibitorsrab GTP-Binding ProteinsSignal TransductionErbB ReceptorsErlotinib HydrochlorideGefitinibGerminal Center KinasesMAP4K2 protein, humanProtein Kinase InhibitorsRAB8A protein, humanrab GTP-Binding ProteinscancerEGFRFGFRRab8Rabin8

Identifiers

PMID33092268
PMCPMC7589727
OpenAlexW3093922812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.