Evidence map›Paper›PMID 33092252›Full record

ArticleMolecules (Basel, Switzerland)2020

Affinity of Antifungal Isoxazolo[3,4-

Krzesimir Ciura, Joanna Fedorowicz, Petar Žuvela, Mario Lovrić, Hanna Kapica, Paweł Baranowski, Wiesław Sawicki, Ming Wah Wong, Jarosław Sączewski

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Krzesimir CiuraDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Joanna FedorowiczDepartment of Chemical Technology of Drugs, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Petar ŽuvelaDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
Mario LovrićKnow-Center, Inffeldgasse 13, AT-8010 Graz, Austria.ORCID 0000-0002-3541-9624
Hanna KapicaDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Paweł BaranowskiDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Wiesław SawickiDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Ming Wah WongDepartment of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.ORCID 0000-0003-2162-1220
Jarosław SączewskiDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Al. Gen. J. Hallera 107, 80-416, Gdańsk, Poland.
Gdańsk Medical University · PLNational University of Singapore · SGKnow Center Research GmbH (Austria) · AT

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego ST3 02-0003/07/518
6 · The paper itself

Abstract

Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the approximation of the processes of absorption, distribution, metabolism, and elimination. Although the lipophilicity of drug candidates is determined using the shake flash method (

Indexed as

Membranes, Artificial1-OctanolAntifungal AgentsChromatography, High Pressure LiquidChromatography, Reverse-PhaseHydrogen-Ion ConcentrationHydrophobic and Hydrophilic InteractionsPhospholipidsPyridinesPyridonesWater1-OctanolAntifungal AgentsMembranes, ArtificialPhospholipidspyridinePyridinesPyridonesWaterIAM-HPLCimmobilized artificial membraneisoxazolo[3,4-b]pyridin-3(1H)-oneisoxazolone

Identifiers

PMID33092252
PMCPMC7587931
OpenAlexW3094134769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.