Evidence map›Paper›PMID 33092235›Full record

ArticleInternational journal of molecular sciences2020

Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma.

Faysal Bin Hamid, Vinod Gopalan, Marco Matos, Cu-Tai Lu, Alfred King-Yin Lam

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Advanced Microfluidics for Single Cell-Based Cancer Research.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Circulating biomarkers for diagnosis and response to therapies in cancer patients.International review of cell and molecular biology · 2025
    Review
  4. Review
  5. Review
  6. Biological factors driving colorectal cancer metastasis.World journal of gastrointestinal oncology · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Faysal Bin HamidCancer Molecular Pathology, School of Medicine, Griffith University, Gold Coast, QLD 4222, Australia.
Vinod GopalanCancer Molecular Pathology, School of Medicine, Griffith University, Gold Coast, QLD 4222, Australia.
Marco MatosOncology, Gold Coast University Hospital, Gold Coast, QLD 4215, Australia.
Cu-Tai LuColorectal Surgery, Gold Coast University Hospital, Gold Coast, QLD 4215, Australia.
Alfred King-Yin LamCancer Molecular Pathology, School of Medicine, Griffith University, Gold Coast, QLD 4222, Australia.ORCID 0000-0003-2771-564X
Griffith University · AUGold Coast Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to isolate and investigate the genetic heterogeneities in single circulating tumour cells (CTCs) from patients with colorectal carcinoma (CRC). Twenty-eight single CTCs were collected from eight patients with CRC using a negative immunomagnetic enrichment method. After validation with glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene expression in 3 colon cancer cell lines, a panel of 19 genes were used to analyse the single CTCs (

Indexed as

Gene Expression Regulation, NeoplasticGenetic HeterogeneityBiomarkers, TumorCell Line, TumorColorectal NeoplasmsGene Expression ProfilingHCT116 CellsHumansNeoplasm StagingNeoplastic Cells, CirculatingReal-Time Polymerase Chain ReactionSingle-Cell AnalysisBiomarkers, Tumorcolorectal carcinomaCTCgene expressionheterogeneitysingle-cell analysis

Identifiers

PMID33092235
PMCPMC7589365
OpenAlexW3093691581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.