ReviewInternational journal of molecular sciences2020
Mediator Complex: A Pivotal Regulator of ABA Signaling Pathway and Abiotic Stress Response in Plants.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 58 citations in OpenAlex.
- A phosphatidic acid-based retrograde signaling pathway responsive to abiotic stress in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Genome-wide analysis of the PRT gene family in rice reveals that OsPRT7 plays a significant role in heat stress response.BMC plant biology · 2026Article
- A comprehensive transcriptomic dataset of Sorghum bicolor seedlings under abiotic stress conditions.Scientific data · 2026Article
- Adaptation of highland barley to drought stress: from phenotypic analysis to physiological and molecular mechanisms.BMC plant biology · 2026Article
- ABA-Induced Transcriptomic Dynamics inPlants (Basel, Switzerland) · 2026Article
- When MED16 Meets Plant Growth, Development, and Stress Response.International journal of molecular sciences · 2026Review
- Review
- Salt stress activates the CDK8-AHL10-SUVH2/9 module to dynamically regulate salt tolerance in Arabidopsis.Nature communications · 2025Article
- Genome-Wide Identification and Expression Analysis of the Mediator Complex Subunit Gene Family in Cassava.International journal of molecular sciences · 2025Article
- Review
- Heterologous expression of Halostachys caspica pathogenesis-related protein 10 increases salt and drought resistance in transgenic Arabidopsis thaliana.Plant molecular biology · 2024Article
- Transcriptome Analysis of Potato Leaves under Oxidative Stress.International journal of molecular sciences · 2024Article
- RhMED15a-like, a subunit of the Mediator complex, is involved in the drought stress response in Rosa hybrida.BMC plant biology · 2024Article
- Comparative phylogenetic analysis of the mediator complex subunit in asparagus bean (Vigna unguiculata ssp. sesquipedialis) and its expression profile under cold stress.BMC genomics · 2024Article
- The 14-3-3 Protein BdGF14a Increases the Transcriptional Regulation Activity of BdbZIP62 to Confer Drought and Salt Resistance in Tobacco.Plants (Basel, Switzerland) · 2024Article
- Strigolactones and abscisic acid interactions affect plant development and response to abiotic stresses.BMC plant biology · 2023Review
- Genome-wide association study presents insights into the genetic architecture of drought tolerance in maize seedlings under field water-deficit conditions.Frontiers in plant science · 2023Article
- Coupling VIGS with Short- and Long-Term Stress Exposure to Understand the Fiskeby III Iron Deficiency Stress Response.International journal of molecular sciences · 2022Article
- ThePlants (Basel, Switzerland) · 2022Article
- Beyond stress response: OST1 opening doors for plants to grow.Stress biology · 2022Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
As an evolutionarily conserved multi-protein complex, the Mediator complex modulates the association between transcription factors and RNA polymerase II to precisely regulate gene transcription. Although numerous studies have shown the diverse functions of Mediator complex in plant development, flowering, hormone signaling, and biotic stress response, its roles in the Abscisic acid (ABA) signaling pathway and abiotic stress response remain largely unclear. It has been recognized that the phytohormone, ABA, plays a predominant role in regulating plant adaption to various abiotic stresses as ABA can trigger extensive changes in the transcriptome to help the plants respond to environmental stimuli. Over the past decade, the Mediator complex has been revealed to play key roles in not only regulating the ABA signaling transduction but also in the abiotic stress responses. In this review, we will summarize current knowledge of the Mediator complex in regulating the plants' response to ABA as well as to the abiotic stresses of cold, drought and high salinity. We will particularly emphasize the involvement of multi-functional subunits of MED25, MED18, MED16, and CDK8 in response to ABA and environmental perturbation. Additionally, we will discuss potential research directions available for further deciphering the role of Mediator complex in regulating ABA and other abiotic stress responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.