Evidence map›Paper›PMID 33092158›Full record

ArticleGenes2020

Genome-Wide Transcriptome Profiling Provides Insight on Cholesterol and Lithocholate Degradation Mechanisms in

Victoria Y Shtratnikova, Mikhail I Schelkunov, Victoria V Fokina, Eugeny Y Bragin, Tatyana G Lobastova, Andrey A Shutov, Alexey V Kazantsev, Marina V Donova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Degradation of CCurrent microbiology · 2025
    Article
  2. Molecules (Basel, Switzerland) · 2023
    Review
  3. Insight into Different Stages of Steroid Degradation in ThermophilicInternational journal of molecular sciences · 2022
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Victoria Y ShtratnikovaBelozersky Research Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-3118-7977
Mikhail I SchelkunovSkolkovo Institute of Science and Technology, Moscow 121205, Russia.
Victoria V FokinaG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research of the Russian Academy of Sciences", Pushchino142290, Russia.
Eugeny Y BraginG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research of the Russian Academy of Sciences", Pushchino142290, Russia.
Tatyana G LobastovaG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research of the Russian Academy of Sciences", Pushchino142290, Russia.
Andrey A ShutovG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research of the Russian Academy of Sciences", Pushchino142290, Russia.ORCID 0000-0002-9501-8072
Alexey V KazantsevChemistry Department, Lomonosov Moscow State University, Moscow 119991, Russia.
Marina V DonovaG.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Federal Research Center "Pushchino Center for Biological Research of the Russian Academy of Sciences", Pushchino142290, Russia.
G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms · RULomonosov Moscow State University · RUSkolkovo Institute of Science and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid microbial degradation plays a significant ecological role for biomass decomposition and removal/detoxification of steroid pollutants. In this study, the initial steps of cholesterol degradation and lithocholate bioconversion by a strain with enhanced 3-ketosteroid dehydrogenase (3-KSD) activity,

Indexed as

Gene Expression Regulation, BacterialGenome, BacterialTranscriptomeActinobacteriaBacterial ProteinsCholesterolComputational BiologyGene Expression ProfilingGenome-Wide Association StudyLithocholic AcidBacterial ProteinsCholesterolLithocholic Acidactinobacteriabacterial transcriptomicsNGSsteroid bioconversiontranscriptional factors

Identifiers

PMID33092158
PMCPMC7593942
OpenAlexW3094428576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.