Evidence map›Paper›PMID 33092129›Full record

ArticleMolecules (Basel, Switzerland)2020

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics.

Anna O Pinson, Dakota L Pouncey, Mary A Schleiff, William E Fantegrossi, Paul L Prather, Anna Radominska-Pandya, Gunnar Boysen, Grover P Miller

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna O PinsonDepartment of Chemistry and Biochemistry, Harding University, Searcy, AR 72149, USA.
Dakota L PounceyCollege of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Mary A SchleiffDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
William E FantegrossiDepartment of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Paul L PratherDepartment of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Anna Radominska-PandyaDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Gunnar BoysenDepartment of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0001-8364-9881
Grover P MillerDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0002-4743-8187
University of Arkansas for Medical Sciences · USHarding University Main Campus · US

Funding

Understanding Hesitant AdoptersP20GM103429 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Lawrence E Cornett, JERRY WARE · 2012 to 2026
$60.9M
Synthetic Cannabinoid Toxicity: Role of BiotransformationR01DA039143 · NIDA · UNIV OF ARKANSAS FOR MED SCIS · PI PRATHER, PAUL L · 2016 to 2020
$2.9M
Systems Pharmacology and Toxicology Training ProgramT32GM106999 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI PRATHER, PAUL L · 2013 to 2022
$1.4M
Drug Enforcement Agency HHSF223201610079CNIDA NIH HHS DA039143NIGMS NIH HHS P20GM103429NIGMS NIH HHS T32GM106999
6 · The paper itself

Abstract

In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse

Indexed as

AdamantaneCannabinoidsHumansIndazolesKineticsMetabolic Networks and PathwaysMicrosomes, LiverAdamantaneCannabinoidsIndazolesN-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide5F-AKB485F-APINACACB1 receptordrug abusekineticsP450synthetic cannabinoid

Identifiers

PMID33092129
PMCPMC7587938
OpenAlexW3094505599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.